Evidence map›Paper›PMID 14975146›Full record

ArticleBMC genetics2003

Genome-wide linkage analysis of blood pressure under locus heterogeneity.

Xinqun Yang, Kai Wang, Jian Huang, Veronica J Vieland

Abstract read
In one paragraph

Article in BMC genetics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xinqun YangDepartment of Biostatistics, Division of Statistical Genetics, The University of Iowa, Iowa City, USA. xinqun-yang@uiowa.edu
Kai Wang
Jian Huang
Veronica J Vieland

Funding

PHS HHS K01-01541PHS HHS R01-52841
6 · The paper itself

Abstract

We describe a method for mapping quantitative trait loci that allows for locus heterogeneity. A genome-wide linkage analysis of blood pressure was performed using sib-pair data from the Framingham Heart Study. Evidence of linkage was found on four markers (GATA89G08, GATA23D06, GATA14E09, and 049xd2) at a significance level of 0.01. Two of them (GATA14E09 and 049xd2) seem to overlap with linkage signals reported previously, while the other two are not linked to any known signals.

Indexed as

Genetic HeterogeneityGenome, HumanAdult ChildrenBlood PressureChromosomes, Human, Pair 16Chromosomes, Human, Pair 5Chromosomes, Human, Pair 8Cohort StudiesFemaleGenetic LinkageGenetic MarkersHumansLikelihood FunctionsLongitudinal StudiesMaleMatched-Pair AnalysisGenetic Markers

Identifiers

PMID14975146
PMCPMC1866517

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.