SynthesisThe Cochrane database of systematic reviews2004
Interventions to help external cephalic version for breech presentation at term.
Synthesis in The Cochrane database of systematic reviews, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 7 syntheses or guidelines pooled it, 158 citations in OpenAlex.
- A Systematic Review and Meta-analysis of Clinical Trials of Neuraxial, Intravenous, and Inhalational Anesthesia for External Cephalic Version.Anesthesia and analgesia · 2020Pooled it
- Strategies for improving health care seeking for maternal and newborn illnesses in low- and middle-income countries: a systematic review and meta-analysis.Global health action · 2016Pooled it
- Planned caesarean section for term breech delivery.The Cochrane database of systematic reviews · 2015Pooled it
- Interventions for helping to turn term breech babies to head first presentation when using external cephalic version.The Cochrane database of systematic reviews · 2015Pooled it
- Interventions for helping to turn term breech babies to head first presentation when using external cephalic version.The Cochrane database of systematic reviews · 2012Pooled it
- Effect of regional anesthesia on the success rate of external cephalic version: a systematic review and meta-analysis.Obstetrics and gynecology · 2011Pooled it
- Reducing stillbirths: interventions during labour.BMC pregnancy and childbirth · 2009Pooled it
- Atosiban versus fenoterol as a uterine relaxant for external cephalic version: randomised controlled trial.BMJ (Clinical research ed.) · 2017Trial
- The Early External Cephalic Version (ECV) 2 Trial: an international multicentre randomised controlled trial of timing of ECV for breech pregnancies.BJOG : an international journal of obstetrics and gynaecology · 2011Trial
- Evaluation of a decision aid for women with breech presentation at term: a randomised controlled trial [ISRCTN14570598].BJOG : an international journal of obstetrics and gynaecology · 2007Trial
- A Review of the Impact of Obstetric Anesthesia on Maternal and Neonatal Outcomes.Anesthesiology · 2018Review
- Article
- Evidence for perinatal and child health care guidelines in crisis settings: can Cochrane help?BMC public health · 2010Article
- Cost-effectiveness of external cephalic version for term breech presentation.BMC pregnancy and childbirth · 2010Article
- Central neuraxial blockade-assisted external cephalic version in reducing caesarean section rate: systematic review and meta-analysis.Obstetrics and gynecology international · 2009Article
- Optimising reproductive and child health outcomes by building evidence-based research and practice in South East Asia (SEA-ORCHID): study protocol.BMC medical research methodology · 2007Article
- Estimated global resources needed to attain universal coverage of maternal and newborn health services.Bulletin of the World Health Organization · 2007Article
Corrections and comments
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Authors and funding
1 author at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBreech presentation places a fetus at increased risk. The outcome for the baby is improved by planned caesarean section compared with planned vaginal delivery. External cephalic version attempts to reduce the chances of breech presentation at birth, but is not always successful. Tocolytic drugs to relax the uterus as well as other methods have been used in an attempt to facilitate external cephalic version at term.
objectivesTo assess the effects of routine tocolysis, fetal acoustic stimulation, epidural or spinal analgesia and transabdominal amnioinfusion for external cephalic version at term on successful version and measures of pregnancy outcome. SEARCH STRATEGY: The Cochrane Pregnancy and Childbirth Group trials register (September 2003) and the Cochrane Central Register of Controlled Trials (The Cochrane Library, Issue 3, 2003) were searched. SELECTION CRITERIA: Randomised and quasi-randomised trials comparing routine versus selective or no tocolysis; fetal acoustic stimulation in midline fetal spine positions versus dummy or no stimulation; epidural or spinal analgesia versus no regional analgesia; or transabdominal amnioinfusion versus no amnioinfusion for external cephalic version at term. DATA COLLECTION AND ANALYSIS: The reviewer assessed eligibility and trial quality. MAIN
resultsIn six trials, routine tocolysis with beta-stimulants was associated with fewer failures of external cephalic version (relative risk (RR) 0.74, 95% confidence interval (CI) 0.64 to 0.87). The reduction in non-cephalic presentations at birth was not statistically significant. Caesarean sections were reduced (RR 0.85, 95% CI 0.72 to 0.99). In four small trials, sublingual nitroglycerine used as a tocolytic was associated with significant side-effects, and was not found to be effective. Fetal acoustic stimulation in midline fetal spine positions was associated with fewer failures of external cephalic version at term (RR 0.17, 95% CI 0.05 to 0.60). With epidural or spinal analgesia, external cephalic version failure, non-cephalic births and caesarean sections were reduced in two trials but not the other. The overall differences were not statistically significant. No randomised trials of transabdominal amnioinfusion for external cephalic version at term were located. REVIEWER'S
conclusionsRoutine tocolysis appears to reduce the failure rate of external cephalic version at term. There is not enough evidence to evaluate the use of fetal acoustic stimulation in midline fetal spine positions, nor of epidural or spinal analgesia. Large volume intravenous preloading may have contributed to the effectiveness demonstrated in two of the latter trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.