Evidence map›Paper›PMID 14973376›Full record

ReviewJournal of mammary gland biology and neoplasia2003

Interrogating mouse mammary cancer models: insights from gene expression profiling.

Antonio A Fargiano, Kartiki V Desai, Jeffrey E Green

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of mammary gland biology and neoplasia, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Antonio A FargianoTransgenic Oncogenesis Group, Laboratory of Cell Regulation and Carcinogenesis, National Cancer Institute, Bethesda, Maryland 20892, USA.
Kartiki V Desai
Jeffrey E Green

Funding

Transgenic Models for Prostate and Breast CancerZIABC005740 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GREEN, JEFFREY E · 2009 to 2016
$7.8M
TRANSGENIC MODELS FOR PROSTATE AND BREAST CANCERZ01BC005740 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GREEN, JEFFREY E · 1996 to 2008
$4.2M
6 · The paper itself

Abstract

Numerous mouse models for mammary cancer have been developed and characterized based upon their biological, molecular, and histopathological features. In an effort to dissect the molecular anatomy of such models and compare their gene expression profiles to those of human breast cancer, six models representing various oncogenic pathways have been investigated using cDNA microarray technology. Results of these analyses are presented and discussed in the context of technological challenges presented by analyzing data on such a large scale. Further expression profiling coupled with emerging proteomic technologies will more completely define and distinguish mouse models of mammary cancer from each other and provide a comprehensive basis for comparing such models with the human disease they are intended to represent.

Indexed as

Disease Models, AnimalGene Expression ProfilingGene Expression Regulation, NeoplasticAnimalsDisease ProgressionMammary Neoplasms, AnimalMiceOligonucleotide Array Sequence Analysis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.