ReviewJournal of mammary gland biology and neoplasia2003
Using gene expression arrays to elucidate transcriptional profiles underlying prolactin function.
Review in Journal of mammary gland biology and neoplasia, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Review
- Effect of Falcaria Vulgaris on Milk Production Parameters in Female Rats' Mammary Glands.Journal of family & reproductive health · 2018Article
- Prosocial effects of prolactin in male rats: Social recognition, social approach and social learning.Hormones and behavior · 2017Article
- Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells.Breast cancer research : BCR · 2017Article
- Prolactin signaling through focal adhesion complexes is amplified by stiff extracellular matrices in breast cancer cells.Oncotarget · 2016Article
- Modeling prolactin actions in breast cancer in vivo: insights from the NRL-PRL mouse.Advances in experimental medicine and biology · 2015Article
- Article
- Global profiling of prolactin-modulated transcripts in breast cancer in vivo.Molecular cancer · 2013Article
- Stiff collagen matrices increase tumorigenic prolactin signaling in breast cancer cells.The Journal of biological chemistry · 2013Article
- The biology of progesterone receptor in the normal mammary gland and in breast cancer.Molecular and cellular endocrinology · 2012Review
- Functional genomics of endothelial cells treated with anti-angiogenic or angiopreventive drugs.Clinical & experimental metastasis · 2010Review
- Insulin, a key regulator of hormone responsive milk protein synthesis during lactogenesis in murine mammary explants.Functional & integrative genomics · 2010Article
- Global expression profiling reveals regulation of CTGF/CCN2 during lactogenic differentiation.Journal of cell communication and signaling · 2009Article
- Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression.Journal of mammary gland biology and neoplasia · 2008Review
- Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation.Breast cancer research : BCR · 2008Article
- ERalpha-CITED1 co-regulated genes expressed during pubertal mammary gland development: implications for breast cancer prognosis.Oncogene · 2007Article
- The biological functions of the versatile transcription factors STAT3 and STAT5 and new strategies for their targeted inhibition.Journal of mammary gland biology and neoplasia · 2006Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prolactin is an ancient hormone, with different functions in many species. The binding of prolactin to its receptor, a member of the cytokine receptor superfamily, results in the activation of different intracellular signaling pathways, such as JAK2/STAT5, MAP kinase, and PI3K/AKT. How prolactin elicits so many different biological responses remains unclear. Recently, microarray technology has been applied to identify prolactin target genes in different systems. Here, we attempt to summarize and compare the available data. Our comparison of the genes reported to be transcriptionally regulated by prolactin indicates that there are few genes in common between the different tissues. Among the organs studied, mammary and prostate glands displayed the largest number of overlaps in putative prolactin target genes. Some of the candidates have been implicated in tumorigenesis. The relevance and validation of microarray data, as well as comparison of the results obtained by different groups, will be discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.