ArticleThe Plant cell2004
Disparate roles for the regulatory A subunit isoforms in Arabidopsis protein phosphatase 2A.
Article in The Plant cell, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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Who cites it
55 citing papers in PubMed, 113 citations in OpenAlex.
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- The Microtubule-Associated Protein CsTON2 Interacts With CsTRM5 and CsSUN to Regulate Fruit Shape Development in Cucumber.Plant biotechnology journal · 2026Article
- SMXL3 controls multiple aspects of Arabidopsis development via EAR motif-dependent and -independent functions.The Plant journal : for cell and molecular biology · 2026Article
- Selection and validation of suitable reference genes for qPCR expression analysis in youngFrontiers in plant science · 2026Article
- Semiautomatic quantification of 3D Histone H3 phosphorylation signals during cell division in Arabidopsis root meristems.The New phytologist · 2025Article
- Phosphorylated transcription factor PuHB40 mediates ROS-dependent anthocyanin biosynthesis in pear exposed to high light.The Plant cell · 2024Article
- I Choose You: Selecting Accurate Reference Genes for qPCR Expression Analysis in Reproductive Tissues inBiomolecules · 2023Article
- Phosphorylation status of Bβ subunit acts as a switch to regulate the function of phosphatase PP2A in ethylene-mediated root growth inhibition.The New phytologist · 2022Article
- Genome-wide identification and expression analysis of the cucumber PP2C gene family.BMC genomics · 2022Article
- Role of protein phosphatases in the regulation of nitrogen nutrition in plants.Physiology and molecular biology of plants : an international journal of functional plant biology · 2021Review
- Integrated Bioinformatics Analyses ofFrontiers in plant science · 2021Article
- Protein phosphatase 2A promotes stomatal development by stabilizing SPEECHLESS inProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Delay of Germination-1 (DOG1): A Key to Understanding Seed Dormancy.Plants (Basel, Switzerland) · 2020Review
- Trait analysis reveals DOG1 determines initial depth of seed dormancy, but not changes during dormancy cycling that result in seedling emergence timing.The New phytologist · 2020Article
- Salicylic Acid Targets Protein Phosphatase 2A to Attenuate Growth in Plants.Current biology : CB · 2020Article
- Auxin regulates adventitious root formation in tomato cuttings.BMC plant biology · 2019Article
- PP2A Phosphatases Take a Giant Leap in the Post-Genomics Era.Current genomics · 2019Review
- Identification and Expression Profiling of Protein Phosphatases (International journal of molecular sciences · 2019Article
- Characterization ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2018Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The heterotrimeric protein phosphatase 2A (PP2A) complex comprises a catalytic subunit and regulatory A and B subunits that modulate enzyme activity and mediate interactions with other proteins. We report here the results of a systematic analysis of the Arabidopsis (Arabidopsis thaliana) regulatory A subunit gene family, which includes the ROOTS CURL IN NAPHTHYLPHTHALAMIC ACID1 (RCN1), PP2AA2, and PP2AA3 genes. All three A subunit isoforms accumulate in the organs of seedlings and adult plants, suggesting extensive overlap in expression domains. We have isolated pp2aa2 and pp2aa3 mutants and found that their phenotypes are largely normal and do not resemble that of rcn1. Whereas rcn1 pp2aa2 and rcn1 pp2aa3 double mutants exhibit striking abnormalities in all stages of development, the pp2aa2 pp2aa3 double mutant shows only modest defects. Together, these data suggest that RCN1 performs a cardinal role in regulation of phosphatase activity and that PP2AA2 and PP2AA3 functions are unmasked only when RCN1 is absent.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.