ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2004
Quantitative ultrasound measurements of bone: measurement error, discordance, and their effects on longitudinal studies.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 14 citations in OpenAlex.
- Heel quantitative ultrasound (QUS) predicts incident fractures independently of trabecular bone score (TBS), bone mineral density (BMD), and FRAX: the OsteoLaus Study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Article
- Quantitative ultrasound and fracture risk prediction in non-osteoporotic men and women as defined by WHO criteria.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013Article
- Calcaneal quantitative ultrasound as a determinant of bone health status: what properties of bone does it reflect?International journal of medical sciences · 2013Review
- Relationship between calcaneal quantitative ultrasound and hip dual energy X-ray absorptiometry in young healthy men.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2012Article
- The Lichfield bone study: the skeletal response to exercise in healthy young men.Journal of applied physiology (Bethesda, Md. : 1985) · 2012Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The performance of quantitative ultrasound (QUS) for the assessment of osteoporotic fracture must be fully defined if it is to be used in the clinical setting. We have examined the precision and reproducibility of two ultrasound instruments in 1,267 institutionalized elderly men and women (mean age 82.1 and 85.9 years, respectively). Measurement of BUA and VOS was reliable, least significant change for BUA being 2.4% and for VOS 0.3% using the CUBA McCue instrument and 2.7% for BUA using the Metra QUS-2. Importantly, age was not found to influence the precision of either parameter. Comparison of the instruments showed the QUS-2 measures BUA higher than the CUBA by 1.9 dB/MHz (+/-9.55 dB/MHz). Moreover classification of individuals as osteoporotic by machine-derived T-score was different between instruments (kappa = 0.44 in men and kappa = 0.62 in women). Fifty-six residents were remeasured by CUBA after 2.2 years; BUA was observed to decrease by 5.2% (+/-16.5%, p = 0.02) without significant change in VOS, suggesting BUA is more useful in longitudinal studies. In conclusion, ultrasound measurements were highly reliable and sensitive to longitudinal change even in the very elderly. However, diagnosis by T-score criteria was instrument specific, and such criteria should be interpreted with caution in the assessment of fracture risk.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.