ArticleThe Journal of clinical investigation2004
HDL action on the vascular wall: is the answer NO?
Article in The Journal of clinical investigation, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- ALDH2 gene G487A polymorphism and coronary artery disease: a meta-analysis including 5644 participants.Journal of cellular and molecular medicine · 2018Pooled it
- Molecular Mechanisms of Vascular Tone in Exercising Pediatric Populations: A Comprehensive Overview on Endothelial, Antioxidative, Metabolic and Lipoprotein Signaling Molecules.International journal of molecular sciences · 2025Review
- High Density Lipoprotein Reduces Blood Pressure and Protects Spontaneously Hypertensive Rats Against Myocardial Ischemia-Reperfusion Injury in an SR-BI Dependent Manner.Frontiers in cardiovascular medicine · 2022Article
- HDL Composition, Heart Failure, and Its Comorbidities.Frontiers in cardiovascular medicine · 2022Review
- Relationship Between HDL Functional Characteristics and Cardiovascular Health and Potential Impact of Dietary Patterns: A Narrative Review.Nutrients · 2019Review
- Inducing apolipoprotein A-I synthesis to reduce cardiovascular risk: from ASSERT to SUSTAIN and beyond.Archives of medical science : AMS · 2016Article
- MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C.Scientific reports · 2015Article
- Article
- 17β-Estradiol regulates scavenger receptor class BI gene expression via protein kinase C in vascular endothelial cells.Endocrine · 2014Article
- High-density lipoprotein cholesterol efflux, nitration of apolipoprotein A-I, and endothelial function in obese women.The American journal of cardiology · 2012Article
- Endothelial expression of human ABCA1 in mice increases plasma HDL cholesterol and reduces diet-induced atherosclerosis.Journal of lipid research · 2012Article
- Apo a-I modulating therapies.Current cardiology reports · 2011Review
- Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease.The Journal of clinical investigation · 2011Article
- Signal transduction underlying the vascular effects of sphingosine 1-phosphate and sphingosylphosphorylcholine.Naunyn-Schmiedeberg's archives of pharmacology · 2006Review
- High-density lipoprotein hydrolysis by endothelial lipase activates PPARalpha: a candidate mechanism for high-density lipoprotein-mediated repression of leukocyte adhesion.Circulation research · 2006Article
Corrections and comments
- Comment on
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Circulating levels of HDL cholesterol are inversely related to the risk of atherosclerosis, and therapeutic increases in HDL reduce the incidence of cardiovascular events. A new study shows that HDL-associated lysophospholipids stimulate the production of the potent antiatherogenic signaling molecule NO by the vascular endothelium.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.