ArticleJournal of Korean medical science2004
Adult-onset Still's disease with disseminated intravascular coagulation and multiple organ dysfunctions dramatically treated with cyclosporine A.
Article in Journal of Korean medical science, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 49 citations in OpenAlex.
- Adult-onset Still's Disease with Acute Kidney Injury Requiring Hemodialysis: A Case Report and Literature Review.Internal medicine (Tokyo, Japan) · 2023Review
- Hepatitis A virus-associated acute acalculous cholecystitis in an adult-onset Still's disease patient: A case report and review of the literature.World journal of clinical cases · 2023Article
- A Recurrent Case of Adult-onset Still's Disease with Concurrent Acalculous Cholecystitis and Macrophage Activation Syndrome/Hemophagocytic Lymphohistiocytosis Successfully Treated with Combination Immunosuppressive Therapy.Internal medicine (Tokyo, Japan) · 2021Article
- Mechanisms, biomarkers and targets for adult-onset Still's disease.Nature reviews. Rheumatology · 2018Review
- Review
- The Use of Cyclosporine A in Rheumatology: a 2016 Comprehensive Review.Clinical reviews in allergy & immunology · 2017Review
- Treatment of adult-onset Still's disease: a review.Therapeutics and clinical risk management · 2015Review
- Adult-onset Still's disease with disseminated intravascular coagulation and hemophagocytic syndrome: a case report.BMC research notes · 2014Article
- Life-threatening complications of adult-onset Still's disease.Clinical rheumatology · 2014Review
- Acalculous cholecystitis with multiple organ failure and disseminated intravascular coagulation in a patient with adult onset Still's disease.Annals of gastroenterology · 2014Article
- Adult-onset Still disease: a rare disorder with a potentially fatal outcome.Auto- immunity highlights · 2010Article
- Multi-organ failure in adult onset Still's disease: a septic disguise.Clinical rheumatology · 2009Article
- Glucocorticoid and cyclosporine refractory adult onset Still's disease successfully treated with tocilizumab.Clinical rheumatology · 2009Article
- Steroid-refractory severe hepatic failure in adult onset Still's disease responding to cyclosporine.Clinical rheumatology · 2008Article
- Hemophagocytic syndrome in one patient with adult-onset Still's disease. Presentation with febrile neutropenia.Clinical rheumatology · 2007Article
- Adult Onset Still's Disease and Radiotherapy treatment for breast cancer: Case report about management of this rare association and literature review.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation OncologyArticle
- So-called Acute Acalculous Cholecystitis in Macrophage Activation Syndrome.Internal medicine (Tokyo, Japan)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe systemic manifestations of adult onset Still's disease (AOSD) are often fatal and occasionally related to hemophagocytic syndrome (HS). We describe the case of a 49-yr-old woman with AOSD presenting with non-remitting high fever, confusion, jaundice, hepatosplenomegaly, serositis, azotemia, pancytopenia, coagulopathy with disseminated intravascular coagulation (DIC), hyperferritinemia, acute acalculous cholecystitis and ileocolitis noted in computed tomographic images. The patient had a history of herpes zoster developed prior to the admission, but there is no history of diarrhea or abdominal pain. Although bone marrow examination was not performed due to hemorrhagic diathesis, we suspected AOSD-associated HS on the basis of clinical course without detectable infectious agents in cultures or serologic studies. Intravenous immunoglobulin, pulse methylprednisolone, oral cyclosporine A (CsA) and ceftriaxone brought about transient improvement of fever and confusion, but the disease progressed. After increasing CsA dose, all previously mentioned abnormalities disappeared rapidly. Accordingly, we believe that DIC and multiple organ dysfunctions might have been the complications of HS but not that of sepsis, and that CsA can be used as a first-line therapy in case of life-threatening situations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.