Evidence map›Paper›PMID 14966157›Full record

ArticleJournal of neurology, neurosurgery, and psychiatry2004

Prospective validation of a proposal for diagnosis and management of patients attending the emergency department for mild head injury.

A Fabbri, F Servadei, G Marchesini, A M Morselli-Labate, M Dente, T Iervese, M Spada, A Vandelli

Abstract readValidation Study
In one paragraph

Article in Journal of neurology, neurosurgery, and psychiatry, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Mild brain injury and anticoagulants: Less is enough.Neurology. Clinical practice · 2017
    Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Mild traumatic brain injury: part 1: determining the need to scan.Canadian family physician Medecin de famille canadien · 2010
    Article
  11. Article
  12. Review
  13. Outcome after complicated minor head injury.AJNR. American journal of neuroradiology · 2008
    Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

A FabbriDipartimento Emergenza-Urgenza Accettazione, Ospedale GB Morgagni, Azienda Unità Sanitaria Locale di Forlì, Italy. andfabbri@libero.it
F Servadei
G Marchesini
A M Morselli-Labate
M Dente
T Iervese
M Spada
A Vandelli

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn mild head injury, predictors to select patients for computed tomography (CT) and/or to plan proper management are needed. The strength of evidence of published recommendations is insufficient for current use. We assessed the diagnostic accuracy and the clinical validity of the proposal of the Neurotraumatology Committee of the World Federation of Neurosurgical Societies on mild head injury from an emergency department perspective.

methodsIn a three year period, 5578 adolescent and adult subjects were prospectively recruited and managed according to the proposed protocol. Outcome measures were: (a) any post-traumatic lesion; (b) need for neurosurgical intervention; (c) unfavourable outcome (death, permanent vegetative state or severe disability) after six months. The predictive value of a model based on five variables (Glasgow coma score, clinical findings, risk factors, neurological deficits, and skull fracture) was tested by logistic regression analysis.

findingsAt first CT evaluation 327 patients (5.9%) had intracranial post-traumatic lesions. In 16 cases (0.3%) previously undiagnosed lesions were detected after re-evaluation within seven days. Neurosurgical intervention was needed in 71 patients (1.3%) and an unfavourable outcome occurred in 39 cases (0.7%). The area under the ROC curve of the variables in predicting post-traumatic lesions was 0.906 (0.009) (sensitivity 70.0%, specificity 94.1% at best cut off), neurosurgical intervention was 0.926 (0.016) (sensitivity 81.7%, specificity 94.1%), and unfavourable outcome was 0.953 (0.014) (sensitivity 88.1%, specificity 95.1%).

interpretationThe variables prove highly accurate in the prediction of clinically meaningful outcomes, when applied to a consecutive set of patients with mild head injury in the clinical setting of a 1st level emergency department.

Indexed as

Severity of Illness IndexTomography, X-Ray ComputedAdolescentAdultCraniocerebral TraumaEmergency Medical ServicesFemaleHumansMaleMiddle AgedOutcome Assessment, Health CarePatient Care PlanningPrognosisProspective StudiesSensitivity and SpecificityTriage

Identifiers

PMID14966157
PMCPMC1738984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.