ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2004
Pathogens involved in lower respiratory tract infections in general practice.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Azithromycin for acute lower respiratory tract infections.The Cochrane database of systematic reviews · 2015Pooled it
- Diagnostic value of C reactive protein in infections of the lower respiratory tract: systematic review.BMJ (Clinical research ed.) · 2005Pooled it
- Prediction model for pneumonia in primary care patients with an acute respiratory tract infection: role of symptoms, signs, and biomarkers.BMC infectious diseases · 2019Article
- Phylogenetic Concepts and Tools Applied to Epidemiologic Investigations of Infectious Diseases.Microbiology spectrum · 2019Review
- Atypical aetiology in patients hospitalised with community-acquired pneumonia is associated with age, gender and season; a data-analysis on four Dutch cohorts.BMC infectious diseases · 2016Article
- Microorganisms Causing Community-Acquired Acute Bronchitis: The Role of Bacterial Infection.PloS one · 2016Article
- Role of Atypical Pathogens and the Antibiotic Prescription Pattern in Acute Bronchitis: A Multicenter Study in Korea.Journal of Korean medical science · 2015Article
- Limited value of chest radiography in predicting aetiology of lower respiratory tract infection in general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2008Article
- Aetiology and prediction of pneumonia in lower respiratory tract infection in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2007Article
- Improved diagnosis of the etiology of community-acquired pneumonia with real-time polymerase chain reaction.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2005Article
- Diagnosing coughs and colds.The British journal of general practice : the journal of the Royal College of General Practitioners · 2004Article
- A diagnostic rule for the aetiology of lower respiratory tract infections as guidance for antimicrobial treatment.The British journal of general practice : the journal of the Royal College of General Practitioners · 2004Article
- Is dyspraxia a medical condition or a social disorder?The British journal of general practice : the journal of the Royal College of General Practitioners · 2004Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are few investigations into the aetiology of lower respiratory tract infections (LRTIs) in general practice.
aimTo describe the aetiology of LRTI among adult patients in general practice in The Netherlands. DESIGN OF STUDY: Prospective observational study.
settingGeneral practices in the Leiden region, The Netherlands.
methodAdult patients with a defined LRTI were included. Standard medical history and physical examination were performed. Sputum, blood and throat swabs were collected for diagnostic tests. Aetiological diagnosis, categorised as definite or possible, was based on the results of bacterial and viral cultures, serological techniques, and on polymerase chain reaction. Proportions of pathogens causing LRTI were assessed in relation to chest X-ray findings.
resultsA bacterial cause was established in 43 (30%), and a viral cause in 57 (39%) of the 145 patients with a LRTI. Influenza virus A was the most frequently diagnosed microorganism, followed by Haemophilus influenzae, and Mycoplasma pneumoniae. Streptococcus pneumoniae was found in 6% of the patients.
conclusionsPathogens were found in two-thirds of the patients. In half of these patients there was a viral cause. Influenza virus A was the most frequently found pathogen. The treatment with antibiotics of at least one-third of the patients with LRTI was superfluous. This observation should result in changes in the prescription of antibiotics in LRTI.
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Identifiers
14965401PMC1314772What OpenQuestion holds
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