Trial reportInternational journal of impotence research2004
Impairment of shear-stress-mediated vasodilation of cavernous arteries in erectile dysfunction.
Trial report in International journal of impotence research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 22 citations in OpenAlex.
- The effect of vardenafil on endothelial function of brachial and cavernous arteries.International journal of impotence researchTrial
- Relationship between chronic tadalafil administration and improvement of endothelial function in men with erectile dysfunction: a pilot study.International journal of impotence researchTrial
- Characterization of age-related penile microvascular hemodynamic impairment using laser speckle contrast imaging: possible role of increased fibrogenesis.Physiological reports · 2017Article
- Aspects of nitric oxide in health and disease: a focus on hypertension and cardiovascular disease.Journal of clinical hypertension (Greenwich, Conn.) · 2006Review
- Physiological regulation of penile arteries and veins.International journal of impotence researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Penile NO release test (PNORT) has been designed to try to evaluate clinically the penile endothelial function (PEF). The shear-stress flow-mediated vasodilation (FMD) of the cavernous arteries is evaluated in two groups of patients with neurogenic (n=23) and vasculogenic (n=23) erectile dysfunction (ED) by measuring their percent of increase after a 5 min occlusion of the flow. Both groups show an important FMD decrease (17.78+/-11.78 and 17.82+/-13%) as compared to the age-matched control group (n=12) (65.14+/-30.5%, P<0.001). In the vasculogenic and control groups, mean FMD is lower in patients with one or more arterial risk factors(41 vs 67%, P=0.025), and show a positive correlation with the plasmatic levels of bioavailable testosterone (r=0.37, P=0.03) and of DHEA-S (r=0.46, P=0.014). Patients achieving full erection at pharmacological test with visual sexual stimulation have a higher FMD (43.8+/-38%) than those who did not (18.52+/-14.37%, P=0.008). We confirm clinically that PEF is strongly impaired in organic ED linked to neurological, vascular and endocrine factors.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.