ArticleJapanese journal of cancer research : Gann1992
Physical ordering of three polymorphic DNA markers spanning the regions containing a tumor suppressor gene of renal cell carcinoma by three-color fluorescent in situ hybridization.
Article in Japanese journal of cancer research : Gann, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 49 citations in OpenAlex.
- Transforming tumoroids derived from ALK-positive pulmonary adenocarcinoma to squamous cell carcinoma in vivo.Human cell · 2024Article
- Clinical application of a lung cancer organoid (tumoroid) culture system.NPJ precision oncology · 2021Article
- The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase.The Journal of cell biology · 2006Article
- A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.The American journal of pathology · 2002Article
- A novel amplicon at 9p23 - 24 in squamous cell carcinoma of the esophagus that lies proximal to GASC1 and harbors NFIB.Japanese journal of cancer research : Gann · 2001Article
- Molecular cytogenetic analysis of 17 renal cancer cell lines: increased copy number at 5q31-33 in cell lines from nonpapillary carcinomas.Japanese journal of cancer research : Gann · 2000Article
- Deletion mapping on chromosome 1p in well-differentiated gastric cancer.British journal of cancer · 1996Article
- A high-resolution cytogenetic map of human chromosome 12: localization of 195 new cosmid markers by direct R-banding fluorescence in situ hybridization.Human genetics · 1993Article
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3 authors at 1 institution in 1 country.
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Abstract
Fluorescent in situ hybridization (FISH) is a powerful technique for gene mapping and multi-color FISH allows us to determine directly the order of two or more probes on both metaphase and interphase chromosomes. We report the physical ordering of three DNA markers by three-color FISH using two fluorochrome dyes, fluorescein isothiocyanate (FITC; green) and rhodamine (red). The third color was visualized as a pseudo-color (yellow) generated by optical interference with FITC and rhodamine. Using this system we could rapidly determine the order of three polymorphic DNA markers located on the 3p23-p21.2 bands which span a tumor suppressor gene for renal cell carcinoma, lung carcinoma, and several other types of tumors.
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