Evidence map›Paper›PMID 14769260›Full record

ReviewCurrent allergy and asthma reports2004

Oxidative stress in the pathogenesis of asthma.

Russell P Bowler

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. 4-Hydroxynonenal, a Potential Biomarker for Lung Inflammatory Diseases.International journal of molecular sciences · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Oxidative Stress-Related Genetic Variants May Modify Associations of Phthalate Exposures with Asthma.International journal of environmental research and public health · 2017
    Article
  16. Article
  17. Article
  18. Biomarkers in Occupational Asthma.Current allergy and asthma reports · 2016
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Russell P BowlerNational Jewish Medical and Research Center, K736a, 1400 Jackson Street, Denver, CO, 80206, USA. BowlerR@njc.org

Funding

NHLBI NIH HHS HL-04407
6 · The paper itself

Abstract

Asthma affects 5% to 10% of the population of the United States. In asthmatics, oxidative stress occurs not only as a result of inflammation but also from environmental exposure to air pollution. The specific localization of antioxidants in the lung and the adaptive changes during asthma underscore the importance of oxidative stress, and therapeutic interventions that decrease exposure to environmental reactive oxygen species or augment endogenous antioxidant defenses might be beneficial as adjunctive therapies in asthmatic patients.

Indexed as

AntioxidantsAsthmaBronchial HyperreactivityHumansLungOxidative StressReactive Nitrogen SpeciesReactive Oxygen SpeciesUnited StatesAntioxidantsReactive Nitrogen SpeciesReactive Oxygen Species

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.