ArticlePflugers Archiv : European journal of physiology2004
Sarcomere-length dependence of lattice volume and radial mass transfer of myosin cross-bridges in rat papillary muscle.
Article in Pflugers Archiv : European journal of physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 34 citations in OpenAlex.
- Myosin motor dynamics and cardiac function: Insights from in vivo small-angle X-ray scattering and pressure-volume analysis.The Journal of physiology · 2026Article
- Stretch-Induced Increase in CaJournal of the American Heart Association · 2025Article
- Sarcomere length affects Ca2+ sensitivity of contraction in ischemic but not non-ischemic myocardium.The Journal of general physiology · 2023Article
- Functional and structural differences between skinned and intact muscle preparations.The Journal of general physiology · 2022Review
- Using Synchrotron Radiation Imaging Techniques to Elucidate the Actions of Hexarelin in the Heart of Small Animal Models.Frontiers in physiology · 2021Article
- Advanced Methodology and Preliminary Measurements of Molecular and Mechanical Properties of Heart Valves under Dynamic Strain.International journal of molecular sciences · 2020Article
- Effect of myofibril passive elastic properties on the mechanical communication between motor proteins on adjacent sarcomeres.Scientific reports · 2019Article
- Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity.The Journal of general physiology · 2019Article
- Structural and functional impact of troponin C-mediated CaJournal of molecular and cellular cardiology · 2018Article
- Myosin MgADP Release Rate Decreases as Sarcomere Length Increases in Skinned Rat Soleus Muscle Fibers.Biophysical journal · 2016Article
- Myosin heads are displaced from actin filaments in the in situ beating rat heart in early diabetes.Biophysical journal · 2013Article
- Thick-to-thin filament surface distance modulates cross-bridge kinetics in Drosophila flight muscle.Biophysical journal · 2012Article
- Roles for cardiac MyBP-C in maintaining myofilament lattice rigidity and prolonging myosin cross-bridge lifetime.Biophysical journal · 2011Article
- Myosin head orientation: a structural determinant for the Frank-Starling relationship.American journal of physiology. Heart and circulatory physiology · 2011Article
- Effects of sustained length-dependent activation on in situ cross-bridge dynamics in rat hearts.Biophysical journal · 2007Article
- Sarcomere length dependence of rat skinned cardiac myocyte mechanical properties: dependence on myosin heavy chain.The Journal of physiology · 2007Article
- Interfilament spacing is preserved during sarcomere length isometric contractions in rat cardiac trabeculae.Biophysical journal · 2007Article
- Contributions of stretch activation to length-dependent contraction in murine myocardium.The Journal of general physiology · 2006Article
- ATP splitting by half the cross-bridges can explain the twitch energetics of mouse papillary muscle.The Journal of physiology · 2006Article
- An X-Ray diffraction study on mouse cardiac cross-bridge function in vivo: effects of adrenergic {beta}-stimulation.Biophysical journal · 2006Article
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We examined the sarcomere length-dependence of the spacing of the hexagonal lattice of the myofilaments and the mass transfer of myosin cross-bridges during contraction of right ventricular papillary muscle of the rat. The lattice spacing and mass transfer were measured by using X-ray diffraction, and the sarcomere length was monitored by laser diffraction at the same time. Although the lattice spacing and the sarcomere length were inversely related, their relationship was not exactly isovolumic. The cell volume decreased by about 15% when the sarcomere length was shortened from 2.3 micro m to 1.8 micro m. Twitch tension increased with sarcomere length (the Frank-Starling law). At the peak tension, the ratio of the intensity of the (1,0) equatorial reflection to that of the (1,1) reflection was smaller when the tension was greater, showing that the larger tension at a longer sarcomere length accompanies a larger amount of mass transfer of cross-bridges from the thick to the thin filament. The result suggests that the Frank-Starling law is due to an increase in the number of myosin heads attached to actin, not in the average force produced by each head.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.