Evidence map›Paper›PMID 14766863›Full record

ArticleJournal of clinical microbiology2004

Gamma interferon-based immunodiagnosis of tuberculosis: comparison between whole-blood and enzyme-linked immunospot methods.

Elisabeth Schölvinck, Katalin A Wilkinson, Adam O Whelan, Adrian R Martineau, Michael Levin, Robert J Wilkinson

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment.Proceedings of the National Academy of Sciences of the United States of America · 2012
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  11. Neutrophil-mediated innate immune resistance to mycobacteria.The Journal of clinical investigation · 2007
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Elisabeth SchölvinckDepartment of Pediatrics. Wellcome Centre for Research in Clinical Tropical Medicine, Faculty of Medicine, Imperial College London, London W2 1PG.
Katalin A Wilkinson
Adam O Whelan
Adrian R Martineau
Michael Levin
Robert J Wilkinson
Imperial College London · GBNorthwick Park Hospital · GBVeterinary Medicines Directorate · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gamma interferon secretion levels of 52 adults whose T cells had been stimulated with the Mycobacterium tuberculosis antigens CFP-10 and ESAT-6 were measured by enzyme-linked immunospot methods and a whole-blood-based assay. The test results correlated well (r = 0.689, P < 0.0001). Its simple format and use of only small volumes of blood make the whole-blood assay suitable for pediatric practice and field trials.

Indexed as

AdultAntigens, BacterialChildEnzyme-Linked Immunosorbent AssayHumansInterferon-gammaLymphocyte ActivationMycobacterium tuberculosisT-LymphocytesTuberculosisAntigens, BacterialInterferon-gamma

Identifiers

PMID14766863
PMCPMC344457
OpenAlexW2139996374

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.