ArticleApplied and environmental microbiology2004
Integron diversity in heavy-metal-contaminated mine tailings and inferences about integron evolution.
Article in Applied and environmental microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 127 citations in OpenAlex.
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- Novel Mobile Integrons and Strain-Specific Integrase Genes withinMicroorganisms · 2022Article
- Mercury and Antibiotic Resistance Co-Selection inInternational journal of environmental research and public health · 2021Article
- Unravelling the antibiotic and heavy metal resistome of a chronically polluted soil.3 Biotech · 2020Article
- Effects of PVP-coated silver nanoparticles on enzyme activity, bacterial and archaeal community structure and function in a yellow-brown loam soil.Environmental science and pollution research international · 2020Article
- Biostimulation potentials of corn steep liquor in enhanced hydrocarbon degradation in chronically polluted soil.3 Biotech · 2019Article
- Metal-tolerant thermophiles: metals as electron donors and acceptors, toxicity, tolerance and industrial applications.Environmental science and pollution research international · 2018Review
- Extreme Geochemical Conditions and Dispersal Limitation Retard Primary Succession of Microbial Communities in Gold Tailings.Frontiers in microbiology · 2018Article
- Metagenomic insights into effects of spent engine oil perturbation on the microbial community composition and function in a tropical agricultural soil.Environmental science and pollution research international · 2017Article
- Bacterial community and arsenic functional genes diversity in arsenic contaminated soils from different geographic locations.PloS one · 2017Article
- Ammonia-Oligotrophic and Diazotrophic Heavy Metal-Resistant Serratia liquefaciens Strains from Pioneer Plants and Mine Tailings.Microbial ecology · 2016Article
- Diversity of gene cassettes and the abundance of the class 1 integron-integrase gene in sediment polluted by metals.Extremophiles : life under extreme conditions · 2016Article
- Detection of integrons and Staphylococcal Cassette Chromosome (SCCmec) types in Staphylococcus aureus isolated from burn and non-burn patients.International journal of health sciences · 2015Article
- Integron diversity in marine environments.Environmental science and pollution research international · 2015Review
- Characterization of multidrug-resistant Salmonella enterica serovars Indiana and Enteritidis from chickens in Eastern China.PloS one · 2014Article
- The function of integron-associated gene cassettes in Vibrio species: the tip of the iceberg.Frontiers in microbiology · 2013Review
- Substrate utilization of stress tolerant methylotrophs isolated from revegetated heavy metal polluted coalmine spoil.World journal of microbiology & biotechnology · 2013Article
- Analysis of the effect of integrons on drug-resistant Staphylococcus aureus by multiplex PCR detection.Molecular medicine reports · 2013Article
- The gain and loss of chromosomal integron systems in the Treponema species.BMC evolutionary biology · 2013Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Integrons are horizontal gene transfer (HGT) systems containing elements necessary for site-specific recombination and expression of foreign DNA. The overall phylogenetic distribution of integrons and range of genes that can be transferred by integrons are unknown. This report contains an exploration of integrons in an environmental microbial community and an investigation of integron evolution. First, using culture-independent techniques, we explored the diversity of integrons and integron-transferred genes in heavy-metal-contaminated mine tailings. Using degenerate primers, we amplified integron integrase genes from the tailings. We discovered 14 previously undescribed integrase genes, including six novel gene lineages. In addition, we found 11 novel gene cassettes in this sample. One of the gene cassettes that we sequenced is similar to a gene that codes for a step in a pathway for nitroaromatic catabolism, a group of compounds associated with mining activity. This suggests that integrons may be important for gene transfer in response to selective pressures other than the presence of antibiotics. We also investigated the evolution of integrons by statistically comparing the phylogenies of 16S rRNA and integrase genes from the same organisms, using sequences from GenBank and various sequencing projects. We found significant differences between the organismal (16S rRNA) and integrase trees, and we suggest that these differences may be due to HGT.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.