Evidence map›Paper›PMID 14762657›Full record

ArticleDiabetologia2004

The epidemiology of Type 1 diabetes mellitus is not the same in young adults as in children.

K O Kyvik, L Nystrom, F Gorus, M Songini, J Oestman, C Castell, A Green, E Guyrus, C Ionescu-Tirgoviste, P A McKinney and 3 more

Open access · bronzeAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Diabetologia, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 151 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 7 countries.

K O KyvikThe Danish Twin Registry, Epidemiology, Institute of Public Health, University of Southern Denmark, Sdr. Boulevard 23 A, 5000, Odense C, Denmark. kkyvik@health.sdu.dk.
L NystromDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
F GorusThe Belgian Diabetes Registry, Brussels, Belgium.
M SonginiThe Sardinian Diabetes Registry, Diabetes Unit, S. Michele Hospital, Cagliari, Italy.
J OestmanCentre of Metabolism and Endocrinology, Huddinge University Hospital, Karolinska Institute, Sweden.
C CastellAdvisory Committee on Diabetes in Catalonia, Department of Health and Social Security, Autonomous Government of Catalonia, Spain.
A GreenDepartment of Epidemiology and Social Medicine, University of Aarhus, Århus, Denmark.
E GuyrusDepartment of Paediatrics, Faculty of Medicine, University of Pécs, Pécs, Hungary.
C Ionescu-TirgovisteInstitute of Nutrition and Metabolic Diseases "N. Paúlescú", Bucharest, Romania.
P A McKinneyPaediatric Epidemiology Group, University of Leeds, Leeds, UK.
D MichalkovaThe Slovak Diabetes Type 1 Registry, University Hospital, Department of Pediatrics, Bratislava, Slovakia.
R OstrauskasInstitute of Endocrinology, Kaunas University of Medicine, Kaunas, Lithuania.
N T RaymondDepartment of Epidemiology and Public Health, University of Leicester, Leicester, UK.
Aarhus University · DKGovernment of Catalonia · ESInternational Diabetes Federation · BEKarolinska University Hospital · SEUmeå University · SEUniversity Hospital Bratislava · SKUniversity of Leeds · GBUniversity of Leicester · GBUniversity of Pecs · HUUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aims/hypothesisThis prospective study examined the epidemiology of Type 1 diabetes in young adults in Europe.

methodsWe ascertained incident cases of Type 1 diabetes in the 15 to 29 years (both inclusive) age group throughout Europe over a period of 2 years. Diabetes registries in nine countries, in which incidence rates for Type 1 diabetes in the 0 to 14 age group were available, took part. Incidence rates were estimated per 100000 person years and standardised for sex and age. Cumulative incidences per 1000 from birth to age 30 were estimated. Heterogeneity between centres was tested with a Poisson regression model.

resultsA total of 2112 diabetes cases were ascertained in 1996 and 1997, of which 61.4% were considered to be Type 1 diabetes. Completeness of ascertainment varied from 70 to 90%. Standardised incidence varied from 4.8 per 100000 person years to 13.4 per 100000 person years. The male-female ratio was estimated to be one or more, and in the 25 to 29 age group 1.5 or more in all countries. Cumulative incidences for males and females indicate that the former exceeds the latter from age 24. In the two centres with highest childhood incidence, this applied already from 14 years of age. CONCLUSIONS/

interpretationThe incidence of Type 1 diabetes in adults is lower than in children and the range of incidence is also reduced, with a less than threefold variation in adults, against an eightfold variation in children. There is a male excess in incidence, especially in the age group 25 to 29 years.

Indexed as

AdolescentAdultAge FactorsDiabetes Mellitus, Type 1EuropeHumansIncidenceRegistries

Identifiers

PMID14762657
OpenAlexW2018062247

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.