ReviewLangenbeck's archives of surgery2004
Current concept of pathophysiological understanding and natural course of ulcerative colitis.
Review in Langenbeck's archives of surgery, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 24 citations in OpenAlex.
- Shared decision-making in the management of patients with inflammatory bowel disease.World journal of gastroenterology · 2022Review
- State-of-the-art surgery for ulcerative colitis.Langenbeck's archives of surgery · 2021Article
- Golimumab in real-world practice in patients with ulcerative colitis: Twelve-month results.World journal of gastroenterology · 2020Observational
- Inflammatory bowel disease: Efficient remission maintenance is crucial for cost containment.World journal of gastrointestinal pharmacology and therapeutics · 2017Review
- Crotoxin from Crotalus durissus terrificus is able to down-modulate the acute intestinal inflammation in mice.PloS one · 2015Article
- Medication adherence and persistence in the treatment of Canadian ulcerative colitis patients: analyses with the RAMQ database.BMC gastroenterology · 2013Article
- Health-related quality of life in inflammatory bowel disease measured with the generic 15D instrument.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2010Article
- Do we really understand what the immunological disturbances in inflammatory bowel disease mean?World journal of gastroenterology · 2009Review
- Basal lymphoid aggregates in ulcerative colitis colon: a site for regulatory T cell action.Clinical and experimental immunology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAccording to the current paradigm both ulcerative colitis (UC) and Crohn's disease (CD) result from a complex interplay of genetic susceptibility factors, environmental factors, alterations of the physiological intestinal flora and a defective regulation of the intestinal immune system. DISCUSSION: The objective of this review is to give an overview of these factors and mechanisms, including genetic, environmental and microbial factors, with special alterations of relevant cellular components of the intestinal immune system such as T cells, macrophages and epithelial cells will then be addressed. In addition, the most relevant animal model systems that have contributed to our current pathogenetic understanding will be introduced. Clinically, the natural course of UC with special reference to the risk of colorectal cancer will be addressed.
conclusionThe elucidation of pathomechanisms at the level of the intestinal immune system provides the potential for novel, effective treatment strategies. Best surgical management of patients with UC, however, still remains a challenge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.