Evidence map›Paper›PMID 14760514›Full record

Trial reportPsychopharmacology2004

The influence on cognition of the interactions between lecithin, carnitine and carbohydrate.

David Benton, Rachael T Donohoe

Abstract readClinical TrialComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Psychopharmacology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

David BentonDepartment of Psychology, University of Wales-Swansea, SA2 8PP Swansea, Wales, UK. d.benton@swansea.ac.uk
Rachael T Donohoe
Swansea University · GBUniversity of Wales · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is accepted that acetylcholine-mediated neurones modulate memory. As lecithin, carnitine and glucose all influence acetylcholine metabolism, the possibility of synergistic interactions was considered. Four hundred young adult females randomly, and under a double-blind procedure, received capsules for 3 days that contained a placebo, lecithin (1.6 g/day), carnitine (500 mg/day) or carnitine plus lecithin. A battery of cognitive tests was administered prior to taking the capsules, after 3 days of taking the supplements, and for a third time after consuming either a glucose drink or a placebo. Reaction times were more rapid when carnitine and a glucose drink were taken together. Memory was enhanced in those taking a glucose rather than placebo drink. Neither mood nor the ability to sustain attention were influenced by these procedures. The hypothesis that memory would be facilitated by offering supplements of lecithin, carnitine and glucose was not supported.

Indexed as

AdultAffectBeveragesCapsulesCarnitineCognitionDouble-Blind MethodDrug CombinationsDrug SynergismFemaleGlucoseHumansMemoryPhosphatidylcholinesReaction TimeSurveys and QuestionnairesCapsulesCarnitineDrug CombinationsGlucosePhosphatidylcholines

Identifiers

PMID14760514
OpenAlexW1986236152

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.