ReviewCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2004
Salt and water: a simple approach to hyponatremia.
Review in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 80 citations in OpenAlex.
- The Convergence of Ancient Medical Wisdom and Modern Physiology: Sodium Ion Wave Propagation in Endothelial Cells, IL-1 Vascular Pathways, and the Six-Day Progression Pattern of Clinical Symptoms.Advances in experimental medicine and biology · 2026Review
- Article
- Evidence-based hyponatremia management in liver disease.Clinical and molecular hepatology · 2023Review
- [Dysnatremia].Die Anaesthesiologie · 2023Article
- Article
- Efficacy and Safety of Isotonic and Hypotonic Intravenous Maintenance Fluids in Hospitalised Children: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.Children (Basel, Switzerland) · 2021Article
- Sodium Toxicity in the Nutritional Epidemiology and Nutritional Immunology of COVID-19.Medicina (Kaunas, Lithuania) · 2021Article
- Understanding dysnatremia.Journal of clinical monitoring and computing · 2021Article
- "Bowel prep hyponatremia" - a state of acute water intoxication facilitated by low dietary solute intake: case report and literature review.BMC nephrology · 2017Review
- The Syndrome of Inappropriate Secretion of AntiDiuretic Hormone in Patients With Brucellosis.Journal of clinical laboratory analysis · 2015Article
- Intravenous fluids in acute decompensated heart failure.JACC. Heart failure · 2015Article
- Management of hyponatremia.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2014Review
- Hyponatremia caused by excessive intake of water as a form of child abuse.Annals of pediatric endocrinology & metabolism · 2013Article
- Vaptans and hyponatremia in critical patients.Translational medicine @ UniSa · 2012Article
- Central pontine myelinolysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2011Article
- Article
- H2O coma.Neurocritical care · 2007Article
- Hyponatremic encephalopathy caused by desmopressin-induced hyponatremia.Journal of neurology · 2005Article
- Exercise-associated hyponatraemia: a mathematical review.Sports medicine (Auckland, N.Z.) · 2005Review
- Hyponatremia: terminology and more.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2004Article
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
- Erratum issued
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyponatremia is common in both inpatients and outpatients. Medications are often the cause of acute or chronic hyponatremia. Measuring the serum osmolality, urine sodium concentration and urine osmolality will help differentiate among the possible causes. Hyponatremia in the physical states of extracellular fluid (ECF) volume contraction and expansion can be easy to diagnose but often proves difficult to manage. In patients with these states or with normal or near-normal ECF volume, the syndrome of inappropriate secretion of antidiuretic hormone is a diagnosis of exclusion, requiring a thorough search for all other possible causes. Hyponatremia should be corrected at a rate similar to that at which it developed. When symptoms are mild, hyponatremia should be managed conservatively, with therapy aimed at removing the offending cause. When symptoms are severe, therapy should be aimed at more aggressive correction of the serum sodium concentration, typically with intravenous therapy in the inpatient setting.
Indexed as
Identifiers
14757675PMC331389W2171339678What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.