ArticlePlant molecular biology2003
Conservation and divergence of ASK1 and ASK2 gene functions during male meiosis in Arabidopsis thaliana.
Article in Plant molecular biology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 47 citations in OpenAlex.
- Evolution and functional characterization of the MdSKP8 gene as a conserved hub integrating hormone and antioxidant pathways for salt tolerance in apple.Plant cell reports · 2026Article
- Dynamic ASK1 proximity networks uncover SCF-dependent and noncanonical roles in ABA and drought adaptation.bioRxiv : the preprint server for biology · 2025Article
- Article
- CAND1 is required for pollen viability inFrontiers in plant science · 2022Article
- The proteome and phosphoproteome of maize pollen uncovers fertility candidate proteins.Plant molecular biology · 2016Article
- Proteomics and transcriptomics analyses of Arabidopsis floral buds uncover important functions of ARABIDOPSIS SKP1-LIKE1.BMC plant biology · 2016Article
- Basic helix-loop-helix transcription factor BcbHLHpol functions as a positive regulator of pollen development in non-heading Chinese cabbage.Functional & integrative genomics · 2014Article
- Instability in mitochondrial membranes in Polima cytoplasmic male sterility of Brassica rapa ssp. chinensis.Functional & integrative genomics · 2014Article
- Functional redundancy and/or ongoing pseudogenization among F-box protein genes expressed in Arabidopsis male gametophyte.Plant reproduction · 2014Article
- Chromosome segregation in plant meiosis.Frontiers in plant science · 2014Review
- Composition, roles, and regulation of cullin-based ubiquitin e3 ligases.The arabidopsis book · 2014Article
- Arabidopsis Kelch repeat F-box proteins regulate phenylpropanoid biosynthesis via controlling the turnover of phenylalanine ammonia-lyase.The Plant cell · 2013Article
- Article
- Proteome analysis of the wild and YX-1 male sterile mutant anthers of wolfberry (Lycium barbarum L.).PloS one · 2012Article
- A comprehensive analysis of interaction and localization of Arabidopsis SKP1-like (ASK) and F-box (FBX) proteins.PloS one · 2012Article
- Meiosis-specific gene discovery in plants: RNA-Seq applied to isolated Arabidopsis male meiocytes.BMC plant biology · 2010Article
- The Arabidopsis thaliana F-box protein FBL17 is essential for progression through the second mitosis during pollen development.PloS one · 2009Article
- ASK1, a SKP1 homolog, is required for nuclear reorganization, presynaptic homolog juxtaposition and the proper distribution of cohesin during meiosis in Arabidopsis.Plant molecular biology · 2006Article
- Auxin flow in anther filaments is critical for pollen grain development through regulating pollen mitosis.Plant molecular biology · 2006Article
- A molecular portrait of Arabidopsis meiosis.The arabidopsis book · 2006Article
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
Abstract
Selective proteolysis of regulatory proteins mediated by the ubiquitin pathway is an important mechanism for controlling many biological events. The SCF (Skpl-Cullin-F-box protein) class of E3 ubiquitin ligases controls the ubiquitination of a wide variety of substrates, thereby mediating their degradation by the 26S proteasome. The Arabidopsis genome contains 21 genes encoding Skp1-like proteins that are named as ASKs (Arabidopsis Skp1-like). So far, only the ASK1 gene has been characterized genetically, and is known to be required for male meiosis, flower development, and auxin response. The ASK2 gene is most similar to ASK1 in terms of both the amino acid sequence and expression pattern. To compare ASK2 with ASK1 functionally in male meiosis, different transgenic lines over-expressing ASK1 and ASK2 were tested for their ability to complement the male meiosis defect of the ask1-1 mutant. The genomic ASK1 rescued the ask1-1 mutant defects. The 35S::ASK1 transgene restored male fertility to the ask1-1 mutant, although the percentages of normal pollen grains and tetrads were reduced. 35S::ASK2 lines in the ask1-1 background exhibited partial fertility with even fewer normal pollen grains and tetrads than those of the 35S::ASK1 lines. Detailed analysis of chromosome behavior during male meiosis demonstrated that 35S::ASK1 and 35S::ASK2 lines had different fractions of pollen mother cells undergoing normal meiosis. Our results suggest that ASK2 partially substitutes for ASK1 if expressed at higher than normal levels.
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