Evidence map›Paper›PMID 14755326›Full record

ReviewThe Journal of clinical investigation2004

Helicobacter pylori persistence: biology and disease.

Martin J Blaser, John C Atherton

Abstract readReview
In one paragraph

Review in The Journal of clinical investigation, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 364 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
364citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

364 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Antibiotics (Basel, Switzerland) · 2026
    Review
  7. Beyond the Stomach: Exploring the Role ofExpert reviews in molecular medicine · 2026
    Review
  8. Review
  9. Preventive Effect ofGut and liver · 2026
    Observational
  10. Review
  11. Distinct Modulation ofBiomolecules · 2026
    Article
  12. Microorganisms · 2025
    Article
  13. Review
  14. Article
  15. BMJ open gastroenterology · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

304 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Martin J BlaserDepartment of Medicine, New York University School of Medicine, and New York Harbor Veterans Affairs Medical Center, New York 10016, USA. martin.blaser@med.nyu.edu
John C Atherton

Funding

MATHEMATICAL MODELS OF H PYLORI GASTRIC COLONIZATIONR01GM063270 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BLASER, MARTIN J · 2000 to 2013
$3.1M
Bacterial flora in normal esophagus &reflux disordersR01CA097946 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PEI, ZHIHENG · 2002 to 2005
$950k
H PYLORI RECOMBINATION AND GASTRIC COLONIZATIONR01DK053707 · NIDDK · VANDERBILT UNIVERSITY · PI BLASER, MARTIN J · 1997 to 2001
$475k
Role of H. Pylori Infection in Esophageal AdenocarcinomaR21DK063603 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TCHOU-WONG, KAM-MENG · 2002 to 2003
$338k
NCI NIH HHS R01 CA097946NCI NIH HHS R01CA97946NIDDK NIH HHS R01DK53707NIDDK NIH HHS R21 DK063603NIDDK NIH HHS R21DK063603NIGMS NIH HHS R01 GM063270NIGMS NIH HHS R01GM63270
6 · The paper itself

Abstract

Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from person to person and to persistently colonize the stomach. Their population structure is a model for the ecology of the indigenous microbiota. A well-choreographed equilibrium between bacterial effectors and host responses permits microbial persistence and health of the host but confers risk of serious diseases, including peptic ulceration and gastric neoplasia.

Indexed as

GhrelinHelicobacter InfectionsHelicobacter pyloriHumansInflammationLeptinPeptide HormonesStomachStomach DiseasesVirulenceGhrelinLeptinPeptide Hormones

Identifiers

PMID14755326
PMCPMC324548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.