ArticleAnalytical chemistry2004
Noninvasive continuous monitoring of physiological glucose using a monosaccharide-sensing contact lens.
Article in Analytical chemistry, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 151 citations in OpenAlex.
- Optical Contact Lenses Biosensors.ACS sensors · 2025Review
- Luminescence Probes in Bio-Applications: From Principle to Practice.Biosensors · 2024Review
- Insight into continuous glucose monitoring: from medical basics to commercialized devices.Mikrochimica acta · 2023Review
- Fluorescence Sensing Technologies for Ophthalmic Diagnosis.ACS sensors · 2022Review
- Wearable Smart Contact Lenses for Continual Glucose Monitoring: A Review.Frontiers in medicine · 2022Review
- Ophthalmic Sensors and Drug Delivery.ACS sensors · 2021Review
- Big data and machine learning for materials science.Discover materials · 2021Review
- Fluorescent contact lens for continuous non-invasive measurements of sodium and chloride ion concentrations in tears.Analytical biochemistry · 2020Article
- Oriented boronate affinity-imprinted inverse opal hydrogel for glycoprotein assay via colorimetry.Mikrochimica acta · 2020Article
- Multifunctional materials for implantable and wearable photonic healthcare devices.Nature reviews. Materials · 2020Article
- Conjunctival dysbiosis in mucosa-associated lymphoid tissue lymphoma.Scientific reports · 2019Article
- Innovative Development of Contact Lenses.Cornea · 2018Review
- Contact-Lens Biosensors.Sensors (Basel, Switzerland) · 2018Review
- Glucose Sensing with Phenylboronic Acid Functionalized Hydrogel-Based Optical Diffusers.ACS nano · 2018Article
- Glucose Sensing for Diabetes Monitoring: Recent Developments.Sensors (Basel, Switzerland) · 2017Review
- Method for analysis of different oligosacchiride structures.Journal of fluorescence · 2012Article
- Nanogold plasmon resonance-based glucose sensing. 2. Wavelength-ratiometric resonance light scattering.Analytical chemistry · 2005Article
- Article
- A glucose-sensing contact lens: from bench top to patient.Current opinion in biotechnology · 2005Review
- Boronic acid fluorescent sensors for monosaccharide signaling based on the 6-methoxyquinolinium heterocyclic nucleus: progress toward noninvasive and continuous glucose monitoring.Bioorganic & medicinal chemistry · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
We have tested the feasibility of tear glucose sensing using a daily, disposable contact lens embedded with boronic acid-containing fluorophores as a potential alternative to current invasive glucose-monitoring techniques. Our findings show that our approach may, indeed, be suitable for the continuous monitoring of tear glucose levels in the range 50-500 microM, which track blood glucose levels that are approximately 5-10-fold higher. We compare the response of the boronic acid probes in the contact lens to solution-based measurements and can conclude that both the pH and polarity within the contact lens need to be considered with respect to choosing/designing and optimizing glucose-sensing probes for contact lenses.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.