ArticleActa crystallographica. Section D, Biological crystallography2004
Crystallization and preliminary crystallographic analysis of Mycoplasma arthritidis-derived mitogen complexed with peptide/MHC class II antigen.
Article in Acta crystallographica. Section D, Biological crystallography, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Review
- Crystal structure of the Mycoplasma arthritidis-derived mitogen in apo form reveals a 3D domain-swapped dimer.Journal of molecular biology · 2010Article
- Zinc induces dimerization of the class II major histocompatibility complex molecule that leads to cooperative binding to a superantigen.The Journal of biological chemistry · 2007Article
- Mutagenesis, biochemical, and biophysical characterization of Mycoplasma arthritidis-derived mitogen.Molecular immunology · 2007Article
- A single point mutation changes the crystallization behavior of Mycoplasma arthritidis-derived mitogen.Acta crystallographica. Section F, Structural biology and crystallization communications · 2006Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Mycoplasma arthritidis-derived mitogen (MAM), a bacterial superantigen, has been crystallized in complex with its human receptor, major histocompatibility complex (MHC) class II antigen, by the hanging-drop vapor-diffusion method. Crystals were obtained under three conditions, with ammonium sulfate, phosphate salt and PEG 8000 as the precipitant. The crystals grown under these conditions all belong to space group I222, with the same unit-cell parameters: a = 137.4, b = 178.2, c = 179.6 A. Diffraction data were collected to 3.3 and 3.4 A resolution from crystals of native and selenomethionylated MAM-MHC complexes, respectively. Self- and cross-rotation function calculations suggest the presence of two complex molecules in the asymmetric unit, resulting in a V(M) of 4.0 and a solvent content of 69%. An interpretable electron-density map was produced using a combination of molecular replacement and SAD phasing.
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