ArticleBiophysical journal2004
Impedance analysis and single-channel recordings on nano-black lipid membranes based on porous alumina.
Article in Biophysical journal, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Advancing membrane biology: single-molecule approaches meet model membrane systems.BMB reports · 2025Review
- Multi-oligomeric states of alamethicin ion channel: Assemblies and conductance.Biophysical journal · 2023Article
- Advances in Functionalization of Bioresorbable Nanomembranes and Nanoparticles for Their Use in Biomedicine.International journal of molecular sciences · 2023Review
- Certain, but Not All, Tetraether Lipids from the Thermoacidophilic ArchaeonInternational journal of molecular sciences · 2021Article
- Ceramide-mediation of diffusion in supported lipid bilayers.Chemistry and physics of lipids · 2021Article
- Characterizing the Structure and Interactions of Model Lipid Membranes Using Electrophysiology.Membranes · 2021Review
- Nanoporous thin films in optical waveguide spectroscopy for chemical analytics.Analytical and bioanalytical chemistry · 2020Review
- Nanoporous Anodic Alumina Photonic Crystals for Optical Chemo- and Biosensing: Fundamentals, Advances, and Perspectives.Nanomaterials (Basel, Switzerland) · 2018Review
- Lipid self-assembly and lectin-induced reorganization of the plasma membrane.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Review
- Lipid Bilayer Membrane in a Silicon Based Micron Sized Cavity Accessed by Atomic Force Microscopy and Electrochemical Impedance Spectroscopy.Biosensors · 2017Article
- Electrochemical impedance spectroscopy for black lipid membranes fused with channel protein supported on solid-state nanopore.European biophysics journal : EBJ · 2016Article
- Reconstitution of Human Ion Channels into Solvent-free Lipid Bilayers Enhanced by Centrifugal Forces.Biophysical journal · 2016Article
- Formation of lipid bilayer membrane in a poly(dimethylsiloxane) microchip integrated with a stacked polycarbonate membrane support and an on-site nanoinjector.Biomicrofluidics · 2015Article
- The influence of nanopore dimensions on the electrochemical properties of nanopore arrays studied by impedance spectroscopy.Sensors (Basel, Switzerland) · 2014Article
- Engineering lipid bilayer membranes for protein studies.International journal of molecular sciences · 2013Review
- Photolithographic fabrication of microapertures with well-defined, three-dimensional geometries for suspended lipid membrane studies.Analytical chemistry · 2013Article
- Lipid nanotechnology.International journal of molecular sciences · 2013Article
- Lipid bilayer coated Al(2)O(3) nanopore sensors: towards a hybrid biological solid-state nanopore.Biomedical microdevices · 2011Article
- The M34A mutant of Connexin26 reveals active conductance states in pore-suspending membranes.Journal of structural biology · 2009Article
- Designing artificial cells to harness the biological ion concentration gradient.Nature nanotechnology · 2008Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ordered porous alumina substrates with pore diameters of 55 and 280 nm, respectively, were produced and utilized as a support to prepare membranes suspending the pores of the material. Highly ordered porous alumina was prepared by an anodization process followed by dissolution of the remaining aluminum and alumina at the backside of the pores. The dissolution process of Al(2)O(3) at the backside of the pores was monitored by electrical impedance spectroscopy ensuring the desired sieve-like structure of the porous alumina. One side of the porous material with an area of 7 mm(2) was coated with a thin gold layer followed by chemisorption of 1,2-dipalmitoyl-sn-glycero-3-phosphothioethanol. The hydrophobic monolayer on top of the upper surface was a prerequisite for the formation of suspending membranes, termed nano-black lipid membranes (nano-BLMs). The formation process, and long-term and mechanical stability of the nano-BLMs were followed by electrical impedance spectroscopy indicating the formation of lipid bilayers with typical specific membrane capacitances of (0.65 +/- 0.2) micro F/cm(2) and membrane resistances of up to 1.6 x 10(8) Omega cm(2). These high membrane resistances allowed for single-channel recordings. Gramicidin as well as alamethicin was successfully inserted into the nano-BLMs exhibiting characteristic conductance states.
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