ArticleBiophysical journal2004
Correlation of AFM and SFA measurements concerning the stability of supported lipid bilayers.
Article in Biophysical journal, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 75 citations in OpenAlex.
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- Native Function of the Bacterial Ion Channel SthK in a Sparsely Tethered Lipid Bilayer Membrane Architecture.The journal of physical chemistry. B · 2023Article
- Insight into the Impact of Oxidative Stress on the Barrier Properties of Lipid Bilayer Models.International journal of molecular sciences · 2022Article
- Liposomes: Structure, Biomedical Applications, and Stability Parameters With Emphasis on Cholesterol.Frontiers in bioengineering and biotechnology · 2021Review
- Interactions of particulate matter and pulmonary surfactant: Implications for human health.Advances in colloid and interface science · 2020Review
- Single lipid extraction: the anchoring strength of cholesterol in liquid-ordered and liquid-disordered phases.Biophysical journal · 2014Article
- The nanomechanical properties of lipid membranes are significantly influenced by the presence of ethanol.Biophysical journal · 2013Article
- Preparation of DOPC and DPPC Supported Planar Lipid Bilayers for Atomic Force Microscopy and Atomic Force Spectroscopy.International journal of molecular sciences · 2013Article
- Electrostatically mediated liposome fusion and lipid exchange with a nanoparticle-supported bilayer for control of surface charge, drug containment, and delivery.Journal of the American Chemical Society · 2009Article
- Diffusion in supported lipid bilayers: influence of substrate and preparation technique on the internal dynamics.The European physical journal. E, Soft matter · 2009Article
- Stability and fusion of lipid layers on polyelectrolyte multilayer supports studied by colloidal force spectroscopy.European biophysics journal : EBJ · 2007Article
- Characterization of physical properties of supported phospholipid membranes using imaging ellipsometry at optical wavelengths.Biophysical journal · 2007Article
- Differential stiffness and lipid mobility in the leaflets of purple membranes.Biophysical journal · 2006Article
- Structure, surface interactions, and compressibility of bacterial S-layers through scanning force microscopy and the surface force apparatus.Biophysical journal · 2006Article
- Effect of temperature on the nanomechanics of lipid bilayers studied by force spectroscopy.Biophysical journal · 2005Article
- Effect of ion-binding and chemical phospholipid structure on the nanomechanics of lipid bilayers studied by force spectroscopy.Biophysical journal · 2005Article
- Using the atomic force microscope to study the interaction between two solid supported lipid bilayers and the influence of synapsin I.Biophysical journal · 2004Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Phospholipid bilayers were studied by means of atomic force microscopy (AFM) and a surface force apparatus (SFA). The stability of the supported bilayers was described by the amount of irregularities in the topography of the membrane by means of AFM and by the occurrence of hemifusion in the SFA, which is an indicator of defective bilayers. The bilayers, composed of lipids having the same headgroup but different chain lengths in the two leaflets, were prepared by Langmuir-Blodgett deposition and transferred at different surface pressures. The topography of the supported bilayers in aqueous solution, as imaged by AFM, revealed an increasing number of defects in the supported lipid membranes with decreased deposition pressure of the outer lipid layer. These defects, which appeared in the form of monolayer and bilayer (self-assembled) thick holes within the membrane, were energetically favorable over an evenly depleted bilayer. We found that the quantity of these defects (holes of </=0.5 micro m diameter and covering up to 30% of the surface area) correlated well with the stability of the bilayers as measured by SFA, a truly complementary instrument.
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