ArticleJournal of molecular evolution2003
Phylogeny and self-splicing ability of the plastid tRNA-Leu group I Intron.
Article in Journal of molecular evolution, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 57 citations in OpenAlex.
- Investigations into the Diversity and Distribution of tRNA and Phylogenetics of Translation Factors in Amoebozoa-InfectingViruses · 2025Article
- An overview of RNA splicing and functioning of splicing factors in land plant chloroplasts.RNA biology · 2022Article
- Genomic Rearrangements and Sequence Evolution across Brown Algal Organelles.Genome biology and evolution · 2021Article
- tRNA functional signatures classify plastids as late-branching cyanobacteria.BMC evolutionary biology · 2019Article
- Comparative plastid genomics of Synurophyceae: inverted repeat dynamics and gene content variation.BMC evolutionary biology · 2019Article
- The Chloroplast Genome ofFrontiers in plant science · 2017Article
- Evolutionary Dynamics of Chloroplast Genomes in Low Light: A Case Study of the Endolithic Green Alga Ostreobium quekettii.Genome biology and evolution · 2016Article
- Updating algal evolutionary relationships through plastid genome sequencing: did alveolate plastids emerge through endosymbiosis of an ochrophyte?Scientific reports · 2015Article
- Evolution of the tRNALeu (UAA) Intron and Congruence of Genetic Markers in Lichen-Symbiotic Nostoc.PloS one · 2015Article
- Reconstruction of structural evolution in the trnL intron P6b loop of symbiotic Nostoc (Cyanobacteria).Current genetics · 2012Article
- Plastid genomes of two brown algae, Ectocarpus siliculosus and Fucus vesiculosus: further insights on the evolution of red-algal derived plastids.BMC evolutionary biology · 2009Article
- Group I introns and GNRA tetraloops: remnants of 'The RNA world'?Molecular biology reports · 2008Article
- The complete nucleotide sequence of the cassava (Manihot esculenta) chloroplast genome and the evolution of atpF in Malpighiales: RNA editing and multiple losses of a group II intron.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2008Article
- A CRM domain protein functions dually in group I and group II intron splicing in land plant chloroplasts.The Plant cell · 2007Article
- The complete plastid genome sequence of the parasitic green alga Helicosporidium sp. is highly reduced and structured.BMC biology · 2006Article
- The chloroplast trnT-trnF region in the seed plant lineage Gnetales.Journal of molecular evolution · 2005Article
- Heterogeneity of intron presence or absence in rDNA genes of the lichen species Physcia aipolia and P. stellaris.Current genetics · 2005Article
- Divergent histories of rDNA group I introns in the lichen family Physciaceae.Journal of molecular evolution · 2005Article
- Comparative analysis of the complete plastid genome sequence of the red alga Gracilaria tenuistipitata var. liui provides insights into the evolution of rhodoplasts and their relationship to other plastids.Journal of molecular evolution · 2004Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Group I introns are mobile RNA enzymes (ribozymes) that encode conserved primary and secondary structures required for autocatalysis. The group I intron that interrupts the tRNA-Leu gene in cyanobacteria and plastids is remarkable because it is the oldest known intervening sequence and may have been present in the common ancestor of the cyanobacteria (i.e., 2.7-3.5 billion years old). This intron entered the eukaryotic domain through primary plastid endosymbiosis. We reconstructed the phylogeny of the tRNA-Leu intron and tested the in vitro self-splicing ability of a diverse collection of these ribozymes to address the relationship between intron stability and autocatalysis. Our results suggest that the present-day intron distribution in plastids is best explained by strict vertical transmission, with no intron losses in land plants or a subset of the Stramenopiles (xanthophyceae/phaeophyceae) and frequent loss among green algae, as well as in the red algae and their secondary plastid derivatives (except the xanthophyceae/phaeophyceae lineage). Interestingly, all tested land plant introns could not self-splice in vitro and presumably have become dependent on a host factor to facilitate in vivo excision. The host dependence likely evolved once in the common ancestor of land plants. In all other plastid lineages, these ribozymes could either self-splice or complete only the first step of autocatalysis.
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