ArticleBone marrow transplantation2004
Outbreaks of infectious diseases in stem cell transplant units: a silent cause of death for patients and transplant programmes.
Article in Bone marrow transplantation, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Immunocompromise and early-onset invasive pulmonary aspergillosis in viral pneumonia: a retrospective cohort study.Frontiers in public health · 2025Article
- The Prognostic Factors of Bloodstream Infection in Immunosuppressed Elderly Patients: A Retrospective, Single-center, Five-year Cohort Study.Clinical interventions in aging · 2022Article
- Clinical Characteristics of Bloodstream Infection in Immunosuppressed Patients: A 5-Year Retrospective Cohort Study.Frontiers in cellular and infection microbiology · 2022Article
- Characteristics of viral pneumonia in non-HIV immunocompromised and immunocompetent patients: a retrospective cohort study.BMC infectious diseases · 2021Article
- Taxonomy.Bone marrow transplantation · 2020Article
- The good, the bad and the ugly.Bone marrow transplantation · 2018Article
- Infectious diseases in allogeneic haematopoietic stem cell transplantation: prevention and prophylaxis strategy guidelines 2016.Annals of hematology · 2016Article
- Parainfluenza Virus Infection.Seminars in respiratory and critical care medicine · 2016Review
- Fungal and viral infections after allogeneic hematopoietic transplantation from unrelated donors in adults: improving outcomes over time.Bone marrow transplantation · 2015Article
- Molecular characterization of a respiratory syncytial virus outbreak in a hematology unit in Heidelberg, Germany.Journal of clinical microbiology · 2013Article
- Respiratory viral infections after hematopoietic stem cell transplantation in children.Journal of Korean medical science · 2013Article
- Multifunctional role of human SPLUNC1 in Pseudomonas aeruginosa infection.Infection and immunity · 2013Article
- Fourth European Conference on Infections in Leukaemia (ECIL-4): guidelines for diagnosis and treatment of human respiratory syncytial virus, parainfluenza virus, metapneumovirus, rhinovirus, and coronavirus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013Review
- A parainfluenza-3 outbreak in a SCT unit: sepsis with multi-organ failure and multiple co-pathogens are associated with increased mortality.Bone marrow transplantation · 2011Article
- Evaluation of a clinical scoring system and directed laboratory testing for respiratory virus infection in hematopoietic stem cell transplant recipients.Transplant infectious disease : an official journal of the Transplantation Society · 2011Article
- Molecular epidemiology of a Pseudomonas aeruginosa hospital outbreak driven by a contaminated disinfectant-soap dispenser.PloS one · 2011Article
- Molecular epidemiological investigation of an outbreak of Pseudomonas aeruginosa infection in an SCT unit.Bone marrow transplantation · 2009Article
- Sinus aspergilloma in rheumatoid arthritis before or during tumor necrosis factor-alpha antagonist therapy.Arthritis research & therapy · 2009Article
- Healthcare-associated infections in pediatric cancer patients: results of a prospective surveillance study from university hospitals in Germany and Switzerland.BMC infectious diseases · 2008Article
- Antibiotic cycling to decrease bacterial antibiotic resistance: a 5-year experience on a bone marrow transplant unit.Bone marrow transplantation · 2007Article
Corrections and comments
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Following the closure of the National Blood and Bone Marrow Transplant Unit in Dublin, because of an outbreak of vancomycin-resistant enterococcal infection, a survey was carried out by the EBMT to investigate the occurrence of outbreaks of infection in SCT units and the impact on patient morbidity, mortality and the administration of the transplant programme over a 10-year period from 1991 to 2001. A total of 13 centres reported 23 outbreaks of infection involving 231 patients: 10 bacterial, eight viral and five fungal outbreaks were reported and 56 deaths were attributed to infection. All fungal and bacterial deaths and the majority of viral deaths occurred in allograft recipients. In all outbreaks, the infection was reported to be hospital acquired and in all the viral, and half the bacterial infections, cross-infection was a major factor. All viral, four of 10 bacterial and three of five fungal outbreaks occurred in HEPA filtered rooms. A total of 12 SCT units reported a partial or total closure. The introduction of mandatory quality management systems such as JACIE should result in a change in attitude to 'incident reporting' and together with future surveys should reduce the incidence of infectious outbreaks in SCT units.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.