ArticleThe Plant cell2004
Aux/IAA proteins contain a potent transcriptional repression domain.
Article in The Plant cell, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 273 papers, 1 of them a synthesis that pooled it.
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Who cites it
273 citing papers in PubMed, 1 synthesis or guideline pooled it, 592 citations in OpenAlex.
- Pooled it
- Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026Review
- HHO5 orchestrates dose-dependent feedback regulation of organic versus inorganic nitrogen signaling in Arabidopsis.The Plant cell · 2026Article
- Genome-wide identification and functional characterization of ABA and salt stress responsive AITRs transcriptional repressors genes in sweet potato (Ipomoea batatas).BMC plant biology · 2026Article
- In Silico Comparative Analysis of the Plant Growth Regulators Forchlorfenuron (CPPU) and Strigol (STG) Interacting with the Gibberellin Biosynthetic Enzyme GA3Ox2 and the Auxin Signaling Protein Receptor IAA7.International journal of molecular sciences · 2026Article
- Pathogenic fungus Ustilago maydis exploits the lateral root regulators to induce pluripotency in maize shoots.The New phytologist · 2026Article
- Integrated Metabolome-Transcriptome Profiling Identifies JrMYB8 as a Repressor of Polyphenol Biosynthesis in Walnut (Plants (Basel, Switzerland) · 2026Article
- Genome-Wide Identification and Expression Profiling of theInternational journal of molecular sciences · 2025Article
- Functional characterization of PavIAA6 in sweet cherry: a key regulator of pigmentation, flavor, and nutrient accumulation.BMC plant biology · 2025Article
- Aux/IAAs: specificity and redundancy.Plant signaling & behavior · 2025Review
- SUPERMAN requires its EAR motif to recruit the corepressor TOPLESS and to function as a cadastral regulator in floral patterning.BMC plant biology · 2025Article
- Article
- Systematic analysis of the Aux/IAA gene family in pineapple reveals insights into their structural diversity, expression dynamics, and interaction networks.BMC plant biology · 2025Article
- Domain characteristics, classification and expression profiles in response to various abiotic stresses of four HD-Zip subfamilies in tea plant.BMC plant biology · 2025Article
- The GhWL1-GhH1-GhGA2OX1 Transcriptional Module Regulates Cotton Leaf Morphology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A KNOTTED1-LIKE HOMEOBOX PROTEIN1-interacting transcription factor SlGATA6 maintains the auxin-response gradient to inhibit abscission.Science advances · 2025Article
- Isolation and Functional Characterization of the MADS-Box GeneInternational journal of molecular sciences · 2025Article
- Article
- OUR1/OsbZIP1-Frontiers in plant science · 2025Article
- Article
213 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aux/IAA proteins are short-lived nuclear proteins that repress expression of primary/early auxin response genes in protoplast transfection assays. Repression is thought to result from Aux/IAA proteins dimerizing with auxin response factor (ARF) transcriptional activators that reside on auxin-responsive promoter elements, referred to as AuxREs. Most Aux/IAA proteins contain four conserved domains, designated domains I, II, III, and IV. Domain II and domains III and IV play roles in protein stability and dimerization, respectively. A clear function for domain I had not been established. Results reported here indicate that domain I in Aux/IAA proteins is an active repression domain that is transferable and dominant over activation domains. An LxLxL motif within domain I is important for conferring repression. The dominance of Aux/IAA repression domains over activation domains in ARF transcriptional activators provides a plausible explanation for the repression of auxin response genes via ARF-Aux/IAA dimerization on auxin-responsive promoters.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.