Evidence map›Paper›PMID 14736641›Full record

ReviewArchives of disease in childhood2004

ESPE/LWPES consensus statement on diabetic ketoacidosis in children and adolescents.

D B Dunger, M A Sperling, C L Acerini, D J Bohn, D Daneman, T P A Danne, N S Glaser, R Hanas, R L Hintz, L L Levitsky and 5 more

Registry-linked trialOpen access · bronzeAbstract readConsensus StatementReview
In one paragraph

Review in Archives of disease in childhood, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03454152 (Electrocardiogram and Echocardiography Changes in Children With Diabetic Ketoacidosis), which is not on this map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03454152 unknown statusnot on this mapstarted 2019, after this paper: background citation

Electrocardiogram and Echocardiography Changes in Children With Diabetic Ketoacidosis

Typeobservational_patient_registrySponsorAssiut UniversityRan2019 to 2020Enrolled60ConditionsPediatric Disorder
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 322 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Efficacy and safety of reduced-dose insulin infusion in pediatric diabetic ketoacidosis: a randomized clinical trial.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

D B DungerUniversity of Cambridge, Department of Paediatrics, Addenbrooke's Hospital, Level 8, Box 116, Cambridge CB2 2QQ, UK. dbd25@cam.ac.uk
M A Sperling
C L Acerini
D J Bohn
D Daneman
T P A Danne
N S Glaser
R Hanas
R L Hintz
L L Levitsky
M O Savage
R C Tasker
J I Wolfsdorf
ESPE
LWPES
Addenbrooke's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic ketoacidosis (DKA) is the leading cause of morbidity and mortality in children with type 1 diabetes mellitus (TIDM). Mortality is predominantly related to the occurrence of cerebral oedema; only a minority of deaths in DKA are attributed to other causes. Cerebral oedema occurs in about 0.3-1% of all episodes of DKA, and its aetiology, pathophysiology, and ideal method of treatment are poorly understood. There is debate as to whether physicians treating DKA can prevent or predict the occurrence of cerebral oedema, and the appropriate site(s) for children with DKA to be managed. There is agreement that prevention of DKA and reduction of its incidence should be a goal in managing children with diabetes.

Indexed as

AdolescentBrain EdemaChildChild, PreschoolDiabetic KetoacidosisEuropeFluid TherapyHumansInsulinPhosphatesPotassium DeficiencyInsulinPhosphates

Identifiers

PMID14736641
PMCPMC1719805
OpenAlexW2156480624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.