ArticleSurgical endoscopy2004
Hematogenous tumor cell dissemination during colonoscopy for colorectal cancer.
Article in Surgical endoscopy, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Self-expanding metallic stent as a bridge to surgery versus emergency surgery for obstructive colorectal cancer: a meta-analysis.Surgical endoscopy · 2012Pooled it
- Effects of prior endoscopic resection on recurrence in patients with T1 colorectal cancer who underwent radical surgery.International journal of colorectal disease · 2023Article
- Vertical tumor margin of endoscopic resection for T1 colorectal carcinoma affects the prognosis of patients undergoing additional surgery.Surgical endoscopy · 2022Article
- Impact of non-curative endoscopic submucosal dissection on short- and long-term outcome of subsequent laparoscopic gastrectomy for pT1 gastric cancer.Surgical endoscopy · 2022Article
- Colon metal stents as a bridge to surgery had no significant effects on the perineural invasion: a retrospective study.World journal of surgical oncology · 2020Article
- Self-expandable metal stent placement versus emergency resection for malignant proximal colon obstructions.Surgical endoscopy · 2017Article
- Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases.Scientific reports · 2017Article
- Does the mobilization of circulating tumour cells during cancer therapy cause metastasis?Nature reviews. Clinical oncology · 2017Review
- Effect of surgical intervention on circulating tumor cells in patients with squamous cell carcinoma of the head and neck using a negative enrichment technology.Head & neck · 2016Article
- A prospective multicenter study on self-expandable metallic stents as a bridge to surgery for malignant colorectal obstruction in Japan: efficacy and safety in 312 patients.Surgical endoscopy · 2016Observational
- Endoscopic stent placement in the management of malignant colonic obstruction: Experiences from two centers.Ulusal cerrahi dergisi · 2015Article
- Long-term oncologic outcomes of endoscopic stenting as a bridge to surgery for malignant colonic obstruction: comparison with emergency surgery.Surgical endoscopy · 2014Article
- Prognostic relevance of minimal residual disease in colorectal cancer.World journal of gastroenterology · 2014Review
- Matrix metalloproteinase-9: a deleterious link between hepatic ischemia-reperfusion and colorectal cancer.World journal of gastroenterology · 2012Article
- Does stenting of left-sided colorectal cancer as a "bridge to surgery" adversely affect oncological outcomes? A comparison with non-obstructing elective left-sided colonic resections.International journal of colorectal disease · 2012Article
- Metastasis: recent discoveries and novel perioperative treatment strategies with particular interest in the hemostatic compound desmopressin.Current pharmaceutical biotechnology · 2011Review
- Multiplex RT-PCR-based detections of CEA, CK20 and EGFR in colorectal cancer patients.World journal of gastroenterology · 2010Article
- Increased detection rate and potential prognostic impact of disseminated tumor cells in patients undergoing endorectal ultrasound for rectal cancer.International journal of colorectal disease · 2007Article
- Additional Surgical Resection After Endoscopic Resection for Patients With High-risk T1 Colorectal Cancer.In vivo (Athens, Greece)Article
- Clinical significance of telomerase activity in peritoneal disseminated cells: gastrointestinal cancers.Molecular medicine (Cambridge, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt has long been suspected that mechanical influences may enhance the release of viable colorectal cancer cells into the circulation. The objective of this study was to determine the extent of hematogenous tumor cell spread in colorectal cancer patients during colonoscopy.
methodsPeripheral venous blood samples were taken before and after colonoscopy from 44 patients with colorectal cancer. Blood samples were examined using a reverse-transcriptase polymerase chain reaction assay to amplify cytokeratin 20 transcripts.
resultsEleven patients with colorectal cancer displayed circulating tumor cells before and after colonoscopy (25%), whereas tumor cells were detected in six of 44 patients (14%) only after the procedure (p = 0.03, McNemar's test: tumor cell detection before after colonoscopy). All control samples consistently tested negative.
conclusionsMechanical forces may result in enhanced release of viable colorectal cancer cells into the circulation; however, the clinical significance of these results needs to be clarified.
Indexed as
Identifiers
14735340What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.