ArticleTrends in cell biology1993
New and cryptic biological messages from RNases.
Article in Trends in cell biology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The trial behind it
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Who cites it
22 citing papers in PubMed.
- Emerging biological functions of ribonuclease 1 and angiogenin.Critical reviews in biochemistry and molecular biology · 2022Review
- Gene therapy as a potential tool for treating neuroblastoma-a focused review.Cancer gene therapy · 2016Review
- Purification and characterization of iso-ribonucleases from a novel thermophilic fungus.International journal of molecular sciences · 2014Article
- Leczyme: a new candidate drug for cancer therapy.BioMed research international · 2014Review
- Sialic acid-binding lectin (leczyme) induces caspase-dependent apoptosis-mediated mitochondrial perturbation in Jurkat cells.International journal of oncology · 2013Article
- Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma.Journal of cellular physiology · 2009Article
- Oligomerization of bovine ribonuclease A: structural and functional features of its multimers.The Biochemical journal · 2004Review
- The structural integrity exerted by N-terminal pyroglutamate is crucial for the cytotoxicity of frog ribonuclease from Rana pipiens.Nucleic acids research · 2003Article
- Ribonuclease inhibitor as an intracellular sentry.Nucleic acids research · 2003Article
- Regulation of ribonuclease expression by estradiol in Rana catesbeiana (Bullfrog).Nucleic acids research · 2002Article
- Cancer chemotherapy--ribonucleases to the rescue.Chemistry & biology · 2001Review
- Article
- Purification and cloning of cytotoxic ribonucleases from Rana catesbeiana (bullfrog).Nucleic acids research · 2000Article
- Mutations abrogating the RNase activity in glycoprotein E(rns) of the pestivirus classical swine fever virus lead to virus attenuation.Journal of virology · 1999Article
- A dimeric mutant of human pancreatic ribonuclease with selective cytotoxicity toward malignant cells.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Ribonucleases endowed with specific toxicity for spermatogenic layers.Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology · 1997Article
- Glycoprotein Erns of pestiviruses induces apoptosis in lymphocytes of several species.Journal of virology · 1997Article
- Catalytic activity of bovine seminal ribonuclease is essential for its immunosuppressive and other biological activities.The Biochemical journal · 1995Article
- RNase inhibition of human immunodeficiency virus infection of H9 cells.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Determination of base specificity of multiple ribonucleases from crude samples.Molecular biology reportsArticle
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
RISBASEs are RNases with surprising biological actions, or unexpected physiological roles, in which they act as external factors that influence cell behaviour. There are RISBASEs involved in host defence, angiogenesis and the control of pollen fertility, and RISBASEs with antitumour and antispermatogenic actions. Here, Guiseppe D'Alessio describes these unusual roles for RNases, and speculates about the mechanisms underlying their actions.
Identifiers
14731764What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.