Evidence map›Paper›PMID 1472867›Full record

ReviewGene expression1992

Discordance between gene regulation in vitro and in vivo.

R N Kitsis, L A Leinwand

Abstract readComparative StudyReview
In one paragraph

Review in Gene expression, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Brain Proteomic Responses to Glucocorticoids and Their Relationship With Transcriptome: A Systematic Meta-Analysis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Pooled it
  2. Article
  3. Impact of Low-Dose CT Radiation on Gene Expression and DNA Integrity.International journal of molecular sciences · 2025
    Article
  4. Article
  5. AnFrontiers in genetics · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

R N KitsisDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461.
L A Leinwand

Funding

MYOSIN GENE DIVERSITY AND FUNCTIONR01GM029090 · NIGMS · YESHIVA UNIVERSITY · PI Leslie Anne Leinwand · 1985 to 2026
$12.3M
VASCULAR CONSIDERATIONS IN CARDIOMYOPATHYP01HL037412 · NHLBI · YESHIVA UNIVERSITY · PI FACTOR, STEPHEN M · 1988 to 1992
–
NHLBI NIH HHS HL 02699NHLBI NIH HHS HL 37412NIGMS NIH HHS GM 29090NIGMS NIH HHS R01 GM029090
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cells, CulturedGene Expression RegulationAnimalsCell Line, TransformedDNADNA, RecombinantHumansMammalsMiceMice, TransgenicTranscription, GeneticTransfectionDNADNA, Recombinant

Identifiers

PMID1472867
PMCPMC6057365

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.