Evidence map›Paper›PMID 14720307›Full record

ArticleBMC immunology2004

Cloning and characterization of deer mouse (Peromyscus maniculatus) cytokine and chemokine cDNAs.

Tony Schountz, Renata Green, Bennett Davenport, Amie Buniger, Tiffany Richens, J Jeffrey Root, Forbes Davidson, Charles H Calisher, Barry J Beaty

Open access · goldAbstract read
In one paragraph

Article in BMC immunology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Regulatory T cell-like responses in deer mice persistently infected with Sin Nombre virus.Proceedings of the National Academy of Sciences of the United States of America · 2007
    Article
  10. Article
  11. Bats: important reservoir hosts of emerging viruses.Clinical microbiology reviews · 2006
    Review
  12. Development of a deer mouse whole-genome radiation hybrid panel and comparative mapping of Mus chromosome 11 loci.Mammalian genome : official journal of the International Mammalian Genome Society · 2006
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tony SchountzDepartment of Biological Sciences, Mesa State College, 1100 North Ave, Grand Junction, CO 81501, USA. tschount@mesastate.edu
Renata Green
Bennett Davenport
Amie Buniger
Tiffany Richens
J Jeffrey Root
Forbes Davidson
Charles H Calisher
Barry J Beaty
Colorado Mesa University · USColorado State University · US

Funding

U.S. Based Collaboration in Emerging Viral and Prion Diseases-26625489N01AI025489 · NIAID · University of Texas Medical Branch · 2004 to 2004
–
NIAID NIH HHS N01 AI025489
6 · The paper itself

Abstract

backgroundSin Nombre virus (SNV) establishes a persistent infection in the deer mouse, Peromyscus maniculatus. A strong antibody response occurs in response to SNV infection, but the role of the innate immune response is unclear. To address this issue, we have initiated an effort to identify and characterize deer mouse cytokine and chemokine genes. Such cytokines and chemokines are involved in various aspects of immunity, including the transition from innate to adaptive responses, type I and type II responses, recruitment of leukocytes to sites of infection, and production of mature cells from bone marrow progenitors.

resultsWe established a colony of SNV antibody-negative deer mice and cloned 11 cytokine and chemokine partial cDNA sequences using directed PCR. Most of the deer mouse sequences were highly conserved with orthologous sequences from other rodent species and functional domains were identified in each putative polypeptide.

conclusionsThe availability of these sequences will allow the examination of the role of these cytokines in deer mouse responses to infection with Sin Nombre virus.

Indexed as

Amino Acid SequenceAnimalsChemokinesCloning, MolecularCytokinesDNA, ComplementaryGranulocyte-Macrophage Colony-Stimulating FactorHumansInterleukinsMolecular Sequence DataPeromyscusReverse Transcriptase Polymerase Chain ReactionSequence AlignmentChemokinesCytokinesDNA, ComplementaryGranulocyte-Macrophage Colony-Stimulating FactorInterleukins

Identifiers

PMID14720307
PMCPMC331403
OpenAlexW1588785067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.