Evidence map›Paper›PMID 14715575›Full record

ArticleClinical and diagnostic laboratory immunology2004

Age-related changes in expression of CXCR4 and CCR5 on peripheral blood leukocytes from uninfected infants born to human immunodeficiency virus type 1-infected mothers.

Sharon Shalekoff, Glenda E Gray, Caroline T Tiemessen

Open access · diamondAbstract read
In one paragraph

Article in Clinical and diagnostic laboratory immunology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Immunity to HIV in Early Life.Frontiers in immunology · 2014
    Review
  8. Article
  9. Immunology of pediatric HIV infection.Immunological reviews · 2013
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sharon ShalekoffAIDS Virus Research Unit, National Institute for Communicable Diseases, and Department of Virology, Johannesburg, South Africa.
Glenda E Gray
Caroline T Tiemessen
University of the Witwatersrand · ZAPerinatal HIV Research Unit · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cross-sectional analysis of human immunodeficiency virus-exposed, uninfected infants revealed high proportions of CXCR4-expressing cells in their cord blood, which declined at 4.5 months and increased between 9 and 15 months to levels approaching those of uninfected adults. Proportions of CCR5-expressing cells, however, were very low in cord blood and subsequently increased with age.

Indexed as

AdultAge FactorsCross-Sectional StudiesFemaleFetal BloodHIV-1HIV InfectionsHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalLeukocytesPregnancyPregnancy Complications, InfectiousReceptors, CCR5Receptors, CXCR4Receptors, CCR5Receptors, CXCR4

Identifiers

PMID14715575
PMCPMC321339
OpenAlexW2111628629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.