Evidence map›Paper›PMID 14715553›Full record

ArticleClinical and diagnostic laboratory immunology2004

Fecal immunoglobulin A antibodies in dogs infected or vaccinated with canine coronavirus.

Nicola Decaro, Annamaria Pratelli, Antonella Tinelli, Vito Martella, Michele Camero, Domenico Buonavoglia, Maria Tempesta, Anna Maria Caroli, Canio Buonavoglia

Open access · diamondAbstract read
In one paragraph

Article in Clinical and diagnostic laboratory immunology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Guideline
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Nicola DecaroDepartment of Animal Health and Well-Being, Faculty of Veterinary Medicine, University of Bari, Bari, Italy. n.decaro@veterinaria.uniba.it
Annamaria Pratelli
Antonella Tinelli
Vito Martella
Michele Camero
Domenico Buonavoglia
Maria Tempesta
Anna Maria Caroli
Canio Buonavoglia
University of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fecal secretory immunoglobulin A (IgA) antibodies in dogs infected or vaccinated with canine coronavirus (CCV) were evaluated by an enzyme-linked immunosorbent assay. The study was carried out with 32 fecal samples collected just before inoculation and at 28 days postinoculation. Five groups were studied: naturally infected dogs, experimentally infected dogs, dogs inoculated with a modified live (ML) CCV vaccine by the intramuscular route, dogs inoculated with an ML CCV vaccine by the oronasal route, and dogs given an inactivated CCV vaccine. Both the naturally and the experimentally infected dogs developed high levels of fecal IgAs. Interestingly, dogs inoculated with the ML CCV vaccine by the oronasal route developed levels of fecal IgA that were higher than those observed in the dogs inoculated with the same CCV vaccine by the intramuscular route or those observed in dogs inoculated with the inactivated vaccine. A relationship between the level of fecal IgAs to CCV and the degree of protection against CCV infection was observed.

Indexed as

AnimalsAntibodies, ViralCoronavirus, CanineCoronavirus InfectionsDog DiseasesDogsEnzyme-Linked Immunosorbent AssayFecesImmunoglobulin AViral VaccinesAntibodies, ViralImmunoglobulin AViral Vaccines

Identifiers

PMID14715553
PMCPMC321341
OpenAlexW2127418495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.