ReviewNeurotoxicity research2003
Human umbilical cord blood (HUCB) cells for central nervous system repair.
Review in Neurotoxicity research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- Blood-based therapies to combat neurodegenerative diseases.Metabolic brain disease · 2024Review
- A Biosafety Study of Human Umbilical Cord Blood Mononuclear Cells Transduced with Adenoviral Vector Carrying Human Vascular Endothelial Growth Factor cDNA In Vitro.Biomedicines · 2023Article
- Human umbilical cord mesenchymal stem cells in diabetes mellitus and its complications: applications and research advances.International journal of medical sciences · 2023Review
- Biodistribution of Infused Human Umbilical Cord Blood Cells in Alzheimer's Disease-Like Murine Model.Cell transplantation · 2016Article
- Stem cells and G-CSF for treating neuroinflammation in traumatic brain injury: aging as a comorbidity factor.Journal of neurosurgical sciences · 2014Review
- Human Umbilical Cord Blood for Transplantation Therapy in Myocardial Infarction.Journal of stem cell research & therapy · 2013Article
- Multiple low-dose infusions of human umbilical cord blood cells improve cognitive impairments and reduce amyloid-β-associated neuropathology in Alzheimer mice.Stem cells and development · 2013Article
- Improvement of Contused Spinal Cord in Rats by Cholinergic-like Neuron Therapy.Iranian Red Crescent medical journal · 2013Article
- Viability and neural differentiation of mesenchymal stem cells derived from the umbilical cord following perinatal asphyxia.Journal of perinatology : official journal of the California Perinatal Association · 2012Article
- Enhancing CNS repair in neurological disease: challenges arising from neurodegeneration and rewiring of the network.CNS drugs · 2011Review
- Systemic delivery of umbilical cord blood cells for stroke therapy: a review.Restorative neurology and neuroscience · 2009Review
- Experimental treatment of stroke in spontaneously hypertensive rats by CD34+ and CD34- cord blood cells.German medical science : GMS e-journal · 2005Article
- Novel mechanisms and approaches in the study of neurodegeneration and neuroprotection. a review.Neurotoxicity research · 2003Review
- Granulocyte-colony stimulating factor and umbilical cord blood cell transplantation: Synergistic therapies for the treatment of traumatic brain injury.Brain circulationReview
- Allogeneic human umbilical cord blood for acute ischemic stroke: Phase I clinical trial.Tzu chi medical journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cellular therapy is a compelling and potential treatment for certain neurological and neurodegenerative diseases as well as a viable treatment for acute injury to the spinal cord and brain. The hematopoietic system offers alternative sources for stem cells compared to those of fetal or embryonic origin. Bone marrow stromal and umbilical cord cells have been used in pre-clinical models of brain injury, directed to differentiate into neural phenotypes, and have been related to functional recovery after engraftment in central nervous system (CNS) injury models. This paper reviews the advantages, utilization and progress of human umbilical cord blood (HUCB) cells in the neural cell transplantation and repair field.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.