ReviewImmunologic research2003
Oral tolerance.
Review in Immunologic research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 68 citations in OpenAlex.
- Microbiome-Mucosal Immunity Nexus: Driving Forces in Respiratory Disease Progression.Journal of microbiology (Seoul, Korea) · 2024Review
- A White Paper on Collagen Hydrolyzates and Ultrahydrolyzates: Potential Supplements to Support Joint Health in Osteoarthritis?Current rheumatology reports · 2021Review
- Secretory IgA in Intestinal Mucosal Secretions as an Adaptive Barrier against Microbial Cells.International journal of molecular sciences · 2020Review
- Peculiarities of the formation and subsequent removal of the circulating immune complexes from the bloodstream during the process of digestion.F1000Research · 2018Article
- Functional heterogeneity of gut-resident regulatory T cells.Clinical & translational immunology · 2017Review
- Immunity by equilibrium.Nature reviews. Immunology · 2016Review
- Protective immunity against Naegleria fowleri infection on mice immunized with the rNfa1 protein using mucosal adjuvants.Parasitology research · 2015Article
- The effect of oral tolerance on the allergic airway response in younger and aged mice.The Journal of asthma : official journal of the Association for the Care of Asthma · 2013Article
- Bacillus subtilis: a temperature resistant and needle free delivery system of immunogens.Human vaccines & immunotherapeutics · 2012Review
- Strategies of mucosal immunotherapy for allergic diseases.Cellular & molecular immunology · 2011Review
- Importance of innate mucosal immunity and the promises it holds.International journal of general medicine · 2011Article
- Mucosal anti-CD3 monoclonal antibody attenuates collagen-induced arthritis that is associated with induction of LAP+ regulatory T cells and is enhanced by administration of an emulsome-based Th2-skewing adjuvant.Journal of immunology (Baltimore, Md. : 1950) · 2010Article
- Oral administration of Alequel, a mixture of autologous colon-extracted proteins for the treatment of Crohn's disease.Therapeutic advances in gastroenterology · 2010Article
- Suppression of Th1 and Th17, but not Th2, responses in a CD8(+) T cell-mediated model of oral tolerance.Mucosal immunology · 2009Article
- Article
- Induction of mucosal tolerance in SLE: a sniff or a sip away from ameliorating lupus?Clinical immunology (Orlando, Fla.) · 2009Review
- Mucosal immunity and protection against HIV/SIV infection: strategies and challenges for vaccine design.International reviews of immunology · 2009Review
- Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25- LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells.Journal of immunology (Baltimore, Md. : 1950) · 2008Article
- Control of experimental autoimmune encephalomyelitis by CD4+ suppressor T cells: peripheral versus in situ immunoregulation.Journal of neuroimmunology · 2007Review
- Vasoactive intestinal polypeptide enhances oral tolerance by regulating both cellular and humoral immune responses.Clinical and experimental immunology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autoimmune conditions caused by injurious immune responses against self-antigens can be ameliorated if the inappropriate responses to self-components that cause tissue injury can be modulated by regulatory cells or shut off via the induction of anergy or via deletion of pathogenic immune responses. Antigen encounter at the gut mucosa can lead to suppression of injurious immune responses to self-antigen via these mechanisms. This type of immunological event is termed oral tolerance. In this review, we examine the mechanisms behind the induction of oral tolerance and provide findings from its use as a form of treatment for autoimmune diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.