Evidence map›Paper›PMID 14705823›Full record

ArticleDigestive diseases and sciences2003

Expression of intercellular adhesion molecule-1 (ICAM- 1) during ischemia-reperfusion in human liver tissue allograft: image analysis by confocal laser scanning microscopy.

Liliane Benkoel, Frank Dodero, Jean Hardwigsen, Anne Marie Benoliel, Pierre Bongrand, Danielle Botta-Fridlund, Yves Patrice Le Treut, Albert Chamlian, Dominique Lombardo

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Article in Digestive diseases and sciences, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Liliane BenkoelINSERM U 559, Faculté de Médecine, 27 boulevard Jean Moulin, 13385 Marseille Cedex 05, France.
Frank Dodero
Jean Hardwigsen
Anne Marie Benoliel
Pierre Bongrand
Danielle Botta-Fridlund
Yves Patrice Le Treut
Albert Chamlian
Dominique Lombardo
Inserm · FRHôpital de la Conception · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied and quantified the effect of ischemia-reperfusion on expression of intercellular adhesion molecule-1 (ICAM-1) on sinusoidal endothelial cells and hepatocyte plasma membranes by means of confocal laser scanning microscopy imaging. We found that ischemia induced an increase in ICAM-1 expression on sinusoidal endothelial cells and hepatocytes. After reperfusion, ICAM-1 expression was increased on sinusoidal endothelial cells, whereas it was unmodified on hepatocytes. On the other hand, ICAM-1 expression was not correlated to ischemia-reperfusion liver injury. Therefore, hepatocellular ischemia-reperfusion injury could be induced by other causes than immune-mediated damages.

Indexed as

AdultCell MembraneEndotheliumFemaleHepatocytesHumansImage Processing, Computer-AssistedIntercellular Adhesion Molecule-1LiverLiver TransplantationMaleMicroscopy, ConfocalMiddle AgedReperfusion InjuryIntercellular Adhesion Molecule-1

Identifiers

PMID14705823
OpenAlexW1977607858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.