Evidence map›Paper›PMID 14704203›Full record

ArticleGenetics2003

MLH1p and MLH3p localize to precociously induced chiasmata of okadaic-acid-treated mouse spermatocytes.

Edyta Marcon, Peter Moens

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 129 citations in OpenAlex.

  1. Article
  2. HEIP1 orchestrates pro-crossover protein activity during mammalian meiosis.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  6. Review
  7. Cell genomics · 2023
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Edyta MarconDepartment of Biology, York University, Toronto, Ontario M3J 1P3, Canada.
Peter Moens
York University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the phosphatase inhibitor, okadaic acid, we induce the precocious onset of the chiasmate stage and under those conditions show that the recombination nodules, MLH1 and MLH3 foci, are localized to the chiasmata. It is concluded that MLH1/3 foci are appropriate markers for the studies of crossovers/chiasmata development and distribution at late meiotic prophase.

Indexed as

Crossing Over, GeneticGenetic MarkersAdaptor Proteins, Signal TransducingAnimalsCarrier ProteinsFemaleMaleMeiosisMiceMutL Protein Homolog 1MutL ProteinsNeoplasm ProteinsNuclear ProteinsOkadaic AcidProphaseRecombination, GeneticAdaptor Proteins, Signal TransducingCarrier ProteinsGenetic MarkersMlh1 protein, mouseMlh3 protein, mouseMutL Protein Homolog 1MutL ProteinsNeoplasm ProteinsNuclear ProteinsOkadaic Acid

Identifiers

PMID14704203
PMCPMC1462919
OpenAlexW2128644010

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.