Evidence map›Paper›PMID 14700112›Full record

ArticleIrish journal of medical science

Appropriateness of gastric antisecretory therapy in hospital practice.

S S Sebastian, N Kernan, A Qasim, C A O'Morain, M Buckley

Abstract read
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In one paragraph

Article in Irish journal of medical science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review of Proton Pump Inhibitor Overuse in the US Veteran Population.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2015
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Inappropriate use of proton pump inhibitors.Irish journal of medical science · 2010
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

S S SebastianDepartment of Gastroenterology, Adelaide Hospital, Tallaght, Dublin, Ireland.
N Kernan
A Qasim
C A O'Morain
M Buckley
Tallaght University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent data indicate an exponential increase in proton pump inhibitor (PPI) prescribing, and concerns are raised regarding the appropriateness of these prescriptions and the financial implications.

aimTo survey the appropriateness of PPI prescription in a cohort of patients in a tertiary referral hospital.

methodsPrescription records of all inpatients on a randomly selected day were reviewed. The appropriateness of prescription and relevant investigations were identified by interview of patients, review of patient records and of a computerised endoscopy records system.

resultsThirty-two per cent (87 of 272) of all patients were on PPIs. A valid indication for therapy was not apparent in 63% of the patients on PPIs with the only predictive factor for inappropriate prescription being increasing age. Only 36 of the 87 patients on PPIs had undergone appropriate investigations for their gastrointestinal symptoms. Gender, age, speciality of admission or duration of hospital stay did not influence the appropriateness of prescription or performance of relevant investigations.

conclusionThere appears to be a widespread and inappropriate use of PPIs in hospital practice.

Indexed as

Drug Utilization ReviewProton Pump InhibitorsAgedDrug PrescriptionsEndoscopy, GastrointestinalEnzyme InhibitorsFemaleHumansInterviews as TopicIrelandMaleMedical RecordsMiddle AgedPractice Patterns, Physicians'Retrospective StudiesEnzyme InhibitorsProton Pump Inhibitors

Identifiers

PMID14700112
OpenAlexW2115130383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.