Evidence map›Paper›PMID 14693563›Full record

ArticleAntimicrobial agents and chemotherapy2004

In vitro postantibiotic effects of rifapentine, isoniazid, and moxifloxacin against Mycobacterium tuberculosis.

Chiu-Yeung Chan, Carrie Au-Yeang, Wing-Wai Yew, Chi-Chiu Leung, Augustine F B Cheng

Abstract readComparative Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Selectivity of the Time-DependentACS chemical biology · 2025
    Article
  5. Next-generation rifamycins for the treatment of mycobacterial infections.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Antimicrobial agents and chemotherapy · 2022
    Article
  8. Article
  9. Antimicrobial agents and chemotherapy · 2021
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. In vitro antimycobacterial activities of capuramycin analogues.Antimicrobial agents and chemotherapy · 2008
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chiu-Yeung ChanDepartment of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories. chiuychan@cuhk.edu.hk
Carrie Au-Yeang
Wing-Wai Yew
Chi-Chiu Leung
Augustine F B Cheng

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postantibiotic effects (PAEs) of rifapentine, isoniazid, and moxifloxacin against Mycobacterium tuberculosis ATCC 27294 were studied using a radiometric culture system. Rifapentine at 20 mg/liter gave the longest PAE (104 h) among the drugs used alone. The combinations of rifapentine plus isoniazid, rifapentine plus moxifloxacin, and isoniazid plus moxifloxacin gave PAEs of 136.5, 59.0, and 8.3 h, respectively.

Indexed as

Anti-Infective AgentsAntitubercular AgentsAza CompoundsDrug CombinationsFluoroquinolonesIsoniazidMicrobial Sensitivity TestsMoxifloxacinMycobacterium tuberculosisQuinolinesRifampinAnti-Infective AgentsAntitubercular AgentsAza CompoundsDrug CombinationsFluoroquinolonesIsoniazidMoxifloxacinQuinolinesRifampinrifapentine

Identifiers

PMID14693563
PMCPMC310201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.