Evidence map›Paper›PMID 14691732›Full record

ArticleAmerican journal of human genetics2004

The effective mutation rate at Y chromosome short tandem repeats, with application to human population-divergence time.

Lev A Zhivotovsky, Peter A Underhill, Cengiz Cinnioğlu, Manfred Kayser, Bharti Morar, Toomas Kivisild, Rosaria Scozzari, Fulvio Cruciani, Giovanni Destro-Bisol, Gabriella Spedini and 7 more

Abstract read
In one paragraph

Article in American journal of human genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 182 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
182citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

182 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  18. Racism and mental health and the role of mental health professionals.European psychiatry : the journal of the Association of European Psychiatrists · 2021
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122 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Lev A ZhivotovskyN. I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia. lev@zhivotovsky.net
Peter A Underhill
Cengiz Cinnioğlu
Manfred Kayser
Bharti Morar
Toomas Kivisild
Rosaria Scozzari
Fulvio Cruciani
Giovanni Destro-Bisol
Gabriella Spedini
Geoffrey K Chambers
Rene J Herrera
Kiau Kiun Yong
David Gresham
Ivailo Tournev
Marcus W Feldman
Luba Kalaydjieva

Funding

VARIATIONS OF HUMAN DNA SEQUENCESP01GM028428 · NIGMS · STANFORD UNIVERSITY · PI CAVALLI-SFORZA, LUIGI L · 1985 to 2004
$6.8M
Regulation of Quiescence in Eukaryotic CellsR01GM107466 · NIGMS · NEW YORK UNIVERSITY · PI GRESHAM, DAVID · 2013 to 2022
$3.0M
POPULATION GENETICS THEORYR01GM028016 · NIGMS · STANFORD UNIVERSITY · PI FELDMAN, MARCUS W · 1985 to 2010
$2.5M
Diversity in Human DNA SequencesR03TW005540 · FIC · STANFORD UNIVERSITY · PI FELDMAN, MARCUS W · 2001 to 2003
$117k
FIC NIH HHS R03 TW005540NIGMS NIH HHS GM28016NIGMS NIH HHS GM28428NIGMS NIH HHS P01 GM028428NIGMS NIH HHS R01 GM028016NIGMS NIH HHS R01 GM107466Wellcome Trust
6 · The paper itself

Abstract

We estimate an effective mutation rate at an average Y chromosome short-tandem repeat locus as 6.9x10-4 per 25 years, with a standard deviation across loci of 5.7x10-4, using data on microsatellite variation within Y chromosome haplogroups defined by unique-event polymorphisms in populations with documented short-term histories, as well as comparative data on worldwide populations at both the Y chromosome and various autosomal loci. This value is used to estimate the times of the African Bantu expansion, the divergence of Polynesian populations (the Maoris, Cook Islanders, and Samoans), and the origin of Gypsy populations from Bulgaria.

Indexed as

MutationChromosome MappingChromosomes, Human, YFemaleGenetic VariationHumansMaleModels, GeneticNew ZealandPolynesiaTandem Repeat SequencesWhite People

Identifiers

PMID14691732
PMCPMC1181912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.