ArticleThe Journal of cell biology2003
Myo4p and She3p are required for cortical ER inheritance in Saccharomyces cerevisiae.
Article in The Journal of cell biology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.
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Who cites it
90 citing papers in PubMed, 186 citations in OpenAlex.
- EASI-ORC: A pipeline for the efficient analysis and segmentation of smFISH images for organelle-RNA colocalization measurements in yeast.Communications biology · 2025Article
- Membrane and organelle rearrangement during ascospore formation in budding yeast.Microbiology and molecular biology reviews : MMBR · 2024Review
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- Overproduction of mycotoxin biosynthetic enzymes triggers Fusarium toxisome-shaped structure formation via endoplasmic reticulum remodeling.PLoS pathogens · 2024Article
- Hitchhiking Across Kingdoms: Cotransport of Cargos in Fungal, Animal, and Plant Cells.Annual review of cell and developmental biology · 2022Review
- Dynamic changes in the association between maternal mRNAs and endoplasmic reticulum during ascidian early embryogenesis.Development genes and evolution · 2022Article
- Programmed cortical ER collapse drives selective ER degradation and inheritance in yeast meiosis.The Journal of cell biology · 2021Article
- Microtubule-independent movement of the fission yeast nucleus.Journal of cell science · 2021Article
- Two- and Three-Dimensional Tracking ofCells · 2020Article
- Cdc42 GTPase regulates ESCRTs in nuclear envelope sealing and ER remodeling.The Journal of cell biology · 2020Article
- Complex Interactions Between Membrane-Bound Organelles, Biomolecular Condensates and the Cytoskeleton.Frontiers in cell and developmental biology · 2020Review
- Organelle Cooperation in Stem Cell Fate: Lysosomes as Emerging Regulators of Cell Identity.Frontiers in cell and developmental biology · 2020Review
- An aggregation-prone mutant of eIF3a forms reversible assemblies escaping spatial control in exponentially growing yeast cells.Current genetics · 2019Article
- Asymmetric Inheritance of Cell Fate Determinants: Focus on RNA.Non-coding RNA · 2019Review
- Myosin-Driven Intracellular Transport.Cold Spring Harbor perspectives in biology · 2018Review
- Sphingolipids activate the endoplasmic reticulum stress surveillance pathway.The Journal of cell biology · 2018Article
- The endoplasmic reticulum is partitioned asymmetrically during mitosis before cell fate selection in proneuronal cells in the earlyMolecular biology of the cell · 2017Article
- Hitchhiking: A Non-Canonical Mode of Microtubule-Based Transport.Trends in cell biology · 2017Review
- ER arrival sites for COPI vesicles localize to hotspots of membrane trafficking.The EMBO journal · 2016Article
- Membrane curvature in cell biology: An integration of molecular mechanisms.The Journal of cell biology · 2016Review
30 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myo4p is a nonessential type V myosin required for the bud tip localization of ASH1 and IST2 mRNA. These mRNAs associate with Myo4p via the She2p and She3p proteins. She3p is an adaptor protein that links Myo4p to its cargo. She2p binds to ASH1 and IST2 mRNA, while She3p binds to both She2p and Myo4p. Here we show that Myo4p and She3p, but not She2p, are required for the inheritance of cortical ER in the budding yeast Saccharomyces cerevisiae. Consistent with this observation, we find that cortical ER inheritance is independent of mRNA transport. Cortical ER is a dynamic network that forms cytoplasmic tubular connections to the nuclear envelope. ER tubules failed to grow when actin polymerization was blocked with the drug latrunculin A (Lat-A). Additionally, a reduction in the number of cytoplasmic ER tubules was observed in Lat-A-treated and myo4Delta cells. Our results suggest that Myo4p and She3p facilitate the growth and orientation of ER tubules.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.