ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2003
Human metapneumovirus-associated lower respiratory tract infections among hospitalized human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 42 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 117 citations in OpenAlex.
- Pandemic influenza in Africa, lessons learned from 1968: a systematic review of the literature.Influenza and other respiratory viruses · 2012Pooled it
- Recommendations for treatment of childhood non-severe pneumonia.The Lancet. Infectious diseases · 2009Guideline
- A role for Streptococcus pneumoniae in virus-associated pneumonia.Nature medicine · 2004Trial
- Avian Metapneumovirus: Virology, Epidemiology, and Insights from a Comparative Analysis with Human Metapneumovirus-A Review.Biomolecules · 2026Review
- Advances in Human Metapneumovirus Research: Clinical Impact, Diagnostic Innovations, and Therapeutic Challenges.Pathogens (Basel, Switzerland) · 2025Review
- Immunological insights into the re-emergence of human metapneumovirus.Current opinion in immunology · 2025Review
- Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- Broad Impact of Exchange Protein Directly Activated by cAMP 2 (EPAC2) on Respiratory Viral Infections.Viruses · 2021Article
- Antibody recognition of the Pneumovirus fusion protein trimer interface.PLoS pathogens · 2020Article
- A Potent Neutralizing Site III-Specific Human Antibody Neutralizes Human MetapneumovirusJournal of virology · 2019Article
- Antibody Epitopes of Pneumovirus Fusion Proteins.Frontiers in immunology · 2019Review
- Human metapneumovirus - what we know now.F1000Research · 2018Review
- The Enduring Challenge of Determining Pneumonia Etiology in Children: Considerations for Future Research Priorities.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Article
- Suppression of human metapneumovirus (HMPV) infection by the innate sensing gene CEACAM1.Oncotarget · 2016Article
- Metapneumovirus Infections and Respiratory Complications.Seminars in respiratory and critical care medicine · 2016Review
- Human metapneumovirus in the preterm neonate: current perspectives.Research and reports in neonatology · 2016Article
- Human metapneumovirus-associated severe acute respiratory illness hospitalisation in HIV-infected and HIV-uninfected South African children and adults.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2015Article
- Prevalence and molecular characterization of human metapneumovirus in influenza a negative sample in Thailand.Journal of clinical laboratory analysis · 2014Article
- Epidemiology, etiology, x-ray features, importance of co-infections and clinical features of viral pneumonia in developing countries.Expert review of anti-infective therapy · 2014Review
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Respiratory tract infections due to human metapneumovirus (hMPV) have been reported worldwide, with the exception of Africa. The prevalence of hMPV infection was studied among human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants who were hospitalized for lower respiratory tract infections (LRTIs). Nasopharyngeal aspirate samples obtained from 81 HIV-1-infected and 110 HIV-1-uninfected infants who had tested negative for other respiratory viruses were selected for investigation. hMPV was detected in 10 HIV-1-uninfected infants (9.1%) and 3 HIV-1-infected infants (3.7%). Compared with the entire cohort of HIV-1-uninfected infants, hMPV was 4.6-fold less common than respiratory syncytial virus, but it was 3.2-fold more common than influenza virus and 2.1-fold more common than parainfluenza virus types 1-3. Genotyping of 7 of 14 isolates revealed the circulation of 2 major phylogenetic groups of the virus, which were similar to those described in North America and Europe.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.