ArticleInfection and immunity2004
Chlamydia-infected cells continue to undergo mitosis and resist induction of apoptosis.
Article in Infection and immunity, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed.
- Chlamydia trachomatis orchestrates multifaceted host cell manipulation for immune evasion.Communications biology · 2026Review
- Preclinical screen for protection efficacy of chlamydial antigens that are immunogenic in humans.Infection and immunity · 2023Article
- Intracellular lifestyle of Chlamydia trachomatis and host-pathogen interactions.Nature reviews. Microbiology · 2023Review
- Review
- Bacteria-Mediated Oncogenesis and the Underlying Molecular Intricacies: What We Know So Far.Frontiers in oncology · 2022Review
- Host cell death during infection with Chlamydia: a double-edged sword.FEMS microbiology reviews · 2021Review
- Chlamydia trachomatis fails to protect its growth niche against pro-apoptotic insults.Cell death and differentiation · 2019Article
- Article
- Clear Victory forFrontiers in microbiology · 2019Review
- Article
- Chlamydia Infection Across Host Species Boundaries Promotes Distinct Sets of Transcribed Anti-Apoptotic Factors.Frontiers in cellular and infection microbiology · 2015Article
- Enterococcus faecalis infection activates phosphatidylinositol 3-kinase signaling to block apoptotic cell death in macrophages.Infection and immunity · 2014Article
- Benzylidene acylhydrazides inhibit chlamydial growth in a type III secretion- and iron chelation-independent manner.Journal of bacteriology · 2014Article
- Chlamydia trachomatis-infected epithelial cells and fibroblasts retain the ability to express surface-presented major histocompatibility complex class I molecules.Infection and immunity · 2014Article
- Transformation of sexually transmitted infection-causing serovars of chlamydia trachomatis using Blasticidin for selection.PloS one · 2013Article
- Identification of a novel nuclear localization signal sequence in Chlamydia trachomatis-secreted hypothetical protein CT311.PloS one · 2013Article
- The role of infectious agents in urogenital cancers.Infectious agents and cancer · 2012Article
- Chlamydia trachomatis antigens recognized in women with tubal factor infertility, normal fertility, and acute infection.Obstetrics and gynecology · 2012Article
- Article
- Induction of protective immunity against Chlamydia muridarum intravaginal infection with a chlamydial glycogen phosphorylase.PloS one · 2012Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Both anti- and proapoptotic activities have been reported to occur during chlamydial infection. To reconcile the apparent controversy, we compared host cell apoptotic responses to infection with 17 different chlamydial serovars and strains. None of the serovars caused any biologically significant apoptosis in the infected host cells. Host cells in chlamydia-infected cultures can continue to undergo DNA synthesis and mitosis. Chlamydia-infected cells are resistant to apoptosis induction, although the extent of the antiapoptotic ability varied between serovars. These observations have demonstrated that an anti- but not proapoptotic activity is the prevailing event in chlamydia-infected cultures.
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Registered trials
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