Evidence map›Paper›PMID 14686781›Full record

ArticleApplied spectroscopy2003

Submicrometer spatial resolution of metal-enhanced fluorescence.

Vincent J Pugh, Henryk Szmacinski, Wayne E Moore, Chris D Geddes, Joseph R Lakowicz

Open access · greenAbstract read
In one paragraph

Article in Applied spectroscopy, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Vincent J PughMicrocosm, Inc., 9140 Guilford Rd., Suite O, Columbia, Maryland 21046-2585, USA. vpugh@microcosm.com
Henryk Szmacinski
Wayne E Moore
Chris D Geddes
Joseph R Lakowicz
Fluor (United States) · USMicrocosm (United States) · USUniversity of Maryland, Baltimore · US

Funding

WHO'S WHO IN FLUORESCENCEP41RR008119 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI BASKAKOV, ILIA V · 1993 to 2006
$7.4M
Nano Metal Enhanced MicroarrayR44CA097569 · NCI · MICROCOSM, INC. · PI NOVIKOVA, SVETLANA IVANOVNA · 2006 to 2008
$948k
Metallic Nanosensor Matrix with Enhanced FluorescenceR43CA097569 · NCI · MICROCOSM, INC. · PI SZMACINSKI, HENRYK · 2002 to 2003
$400k
NCI NIH HHS 1 R3 CA097569-01NCI NIH HHS R43 CA097569NCRR NIH HHS P41 RR008119NCRR NIH HHS RR-08119
6 · The paper itself

Abstract

Enhanced fluorescence emission intensity from fluorescein was observed on glass slides covered with thin films of silver nanoparticles using a confocal laser-scanning microscope. The silver nanoparticle film increased the emission intensity of fluorescein by an average of at least three-fold in the area studied. Statistics are given on the enhancement of individual areas of the silver particle film with a resolution of approximately 210 nm. A histogram of intensity values indicates that the enhancement appears to occur without distinct subpopulations, with the exception that very high intensity subpopulations may occur but could not be resolved. Spatial features with dimensions near or smaller than the resolution limit of the confocal microscope, on the silver nanoparticle slide that enhanced the emission of fluorescein, were found using autocorrelation functions. These spatial features are of the same size as those found from the emission of slides containing silver nanoparticles only. These spatial features do not appear in control slides containing fluorescein without any silver nanoparticles. No long-range spatial ordering of the fluorescence enhancement on chemcially deposited silver nanoparticle slides was detected.

Indexed as

FluorescenceAvidinBiotinFluoresceinMetalsMicroscopy, ConfocalNanotechnologyProteinsSensitivity and SpecificitySerum Albumin, BovineSilverAvidinBiotinFluoresceinMetalsProteinsSerum Albumin, BovineSilver

Identifiers

PMID14686781
PMCPMC6872981
OpenAlexW2068995716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.