Evidence map›Paper›PMID 14682376›Full record

ReviewJournal of neuro-oncology2003

Clinical gene therapy for brain tumors. Liposomal delivery of anticancer molecule to glioma.

Jun Yoshida, Masaaki Mizuno

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neuro-oncology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Gene Delivery in Neuro-Oncology.Current oncology reports · 2017
    Review
  4. Gene therapy for malignant glioma.Molecular and cellular therapies · 2014
    Review
  5. Article
  6. Biomaterials for the central nervous system.Journal of the Royal Society, Interface · 2008
    Review
  7. Drug delivery to brain tumors.Current neurology and neuroscience reports · 2008
    Review
  8. The status of gene therapy for brain tumors.Expert opinion on biological therapy · 2007
    Review
  9. Immunological treatment of liver tumors.World journal of gastroenterology · 2005
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jun YoshidaDepartment of Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, Japan. jyoshida@med.nagoya-u.ac.jp
Masaaki Mizuno

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liposomes are one of the most promising delivery systems for genes, proteins, and other biological molecules and they are expected to become a new therapeutic tool for the treatment of brain tumors, especially malignant gliomas. Until now, transfer of anticancer molecules using liposomes has been studied by a lot of investigators and it has been found to induce regression of experimental gliomas, resulting in establishing some original and effective therapies. Gene therapy using cationic liposomes is also one of them. Here we introduce the advanced medicine for brain tumors using liposomes containing some anticancer molecules (for example, gene, antibody, antisense, or magnetite), based on our basic and clinical research.

Indexed as

AdultAnimalsAntineoplastic AgentsBrain NeoplasmsClinical Trials as TopicDrug Delivery SystemsFemaleGenetic TherapyGliomaHumansInterferon-betaLiposomesAntineoplastic AgentsInterferon-betaLiposomes

Identifiers

PMID14682376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.