ArticleRNA (New York, N.Y.)2004
The RNA binding domain within the nucleoporin Nup153 associates preferentially with single-stranded RNA.
Article in RNA (New York, N.Y.), 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Advances in the understanding of nuclear pore complexes in human diseases.Journal of cancer research and clinical oncology · 2024Review
- The new (dis)order in RNA regulation.Cell communication and signaling : CCS · 2016Review
- The nuclear pore complex and nuclear transport.Cold Spring Harbor perspectives in biology · 2010Review
- Integrase interacts with nucleoporin NUP153 to mediate the nuclear import of human immunodeficiency virus type 1.Journal of virology · 2009Article
- Versatility at the nuclear pore complex: lessons learned from the nucleoporin Nup153.Chromosoma · 2005Review
- The functionally conserved nucleoporins Nup124p from fission yeast and the human Nup153 mediate nuclear import and activity of the Tf1 retrotransposon and HIV-1 Vpr.Molecular biology of the cell · 2005Article
- Distinct functional domains within nucleoporins Nup153 and Nup98 mediate transcription-dependent mobility.Molecular biology of the cell · 2004Article
- Nucleocytoplasmic transport: integrating mRNA production and turnover with export through the nuclear pore.Molecular and cellular biology · 2004Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The nuclear pore protein Nup153 is important for the transport of protein and RNA between the nucleus and cytoplasm. Recently, a novel RNA binding domain (RBD) was mapped within the N-terminal region of Nup153; however, the determinants of RNA association were not characterized. Here we have tested a range of RNAs with different general features to better understand targets recognized by this domain. We have found that the RBD associates with single-stranded RNA with little sequence preference. These results provide new information about a novel RNA binding domain and suggest new models to consider for the contribution of Nup153 to nucleocytoplasmic transport.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.