Evidence map›Paper›PMID 14681470›Full record

ArticleNucleic acids research2004

Pathbase: a database of mutant mouse pathology.

Paul N Schofield, Jonathan B L Bard, Catherine Booth, Jacques Boniver, Vincenzo Covelli, Philippe Delvenne, Michele Ellender, Wilhelm Engstrom, Wolfgang Goessner, Michael Gruenberger and 10 more

Open access · bronzeAbstract read
In one paragraph

Article in Nucleic acids research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 54 citations in OpenAlex.

  1. Bridging mouse and human anatomies; a knowledge-based approach to comparative anatomy for disease model phenotyping.Mammalian genome : official journal of the International Mammalian Genome Society · 2023
    Review
  2. PATHBIO: an international training program for precision mouse phenotyping.Mammalian genome : official journal of the International Mammalian Genome Society · 2020
    Article
  3. Article
  4. Article
  5. Genetic determinants of fibro-osseous lesions in aged inbred mice.Experimental and molecular pathology · 2016
    Article
  6. Article
  7. Article
  8. Article
  9. Training pathologists in mouse pathology.Veterinary pathology · 2012
    Article
  10. The mouse-human anatomy ontology mapping project.Database : the journal of biological databases and curation · 2012
    Article
  11. A flexible, open, decentralized system for digital pathology networks.Studies in health technology and informatics · 2012
    Article
  12. Review
  13. Article
  14. An ontology-based comparative anatomy information system.Artificial intelligence in medicine · 2011
    Article
  15. Article
  16. Article
  17. Article
  18. Where's the mouse info?Veterinary pathology · 2009
    Article
  19. One medicine, one pathology, and the one health concept.Journal of the American Veterinary Medical Association · 2009
    Article
  20. Integrating mouse anatomy and pathology ontologies into a phenotyping database: tools for data capture and training.Mammalian genome : official journal of the International Mammalian Genome Society · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 1 institution in 1 country.

Paul N SchofieldDepartment of Anatomy, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK. ps@mole.bio.cam.ac.uk
Jonathan B L Bard
Catherine Booth
Jacques Boniver
Vincenzo Covelli
Philippe Delvenne
Michele Ellender
Wilhelm Engstrom
Wolfgang Goessner
Michael Gruenberger
Heinz Hoefler
John Hopewell
Mariatheresa Mancuso
Carmel Mothersill
Christopher S Potten
Leticia Quintanilla-Fend
Bjorn Rozell
Hannu Sariola
John P Sundberg
Andrew Ward
University of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathbase is a database that stores images of the abnormal histology associated with spontaneous and induced mutations of both embryonic and adult mice including those produced by transgenesis, targeted mutagenesis and chemical mutagenesis. Images of normal mouse histology and strain-dependent background lesions are also available. The database and the images are publicly accessible (http://www.pathbase.net) and linked by anatomical site, gene and other identifiers to relevant databases; there are also facilities for public comment and record annotation. The database is structured around a novel ontology of mouse disorders (MPATH) and provides high-resolution downloadable images of normal and diseased tissues that are searchable through orthogonal ontologies for pathology, developmental stage, anatomy and gene attributes (GO terms), together with controlled vocabularies for type of genetic manipulation or mutation, genotype and free text annotation for mouse strain and additional attributes. The database is actively curated and data records assessed by pathologists in the Pathbase Consortium before publication. The database interface is designed to have optimal browser and platform compatibility and to interact directly with other web-based mouse genetic resources.

Indexed as

Databases, FactualDiseaseMiceMutationPathologyAnimalsComputational BiologyGenotypeInformation Storage and RetrievalInternetPhenotypeVocabulary, Controlled

Identifiers

PMID14681470
PMCPMC308858
OpenAlexW2134285953

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.